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Alexan (Spironolactone)
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Spironolactone

Alexan is a potassium-sparing diuretic that removes excess fluid from the body in congestive heart failure, cirrhosis of the liver, and kidney disease. It also can be used in combination with other drugs to treat diuretic-induced low potassium (hypokalemia) and high blood pressure. Alexan also is used to counteract the effects of excessive adrenal aldosterone production (hyperaldosteronism) that can occur from a tumor in the adrenal gland or enlarged adrenal glands (hyperplasia of the adrenal glands). Alexan and its active metabolites are specific pharmacologic antagonists of aldosterone, acting primarily through competitive binding of receptors at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tubule. Alexan causes increased amounts of sodium and water to be excreted, while potassium is retained. Alexan acts both as a diuretic and as an antihypertensive drug by this mechanism. It may be given alone or with other diuretic agents that act more proximally in the renal tubule.

Other names for this medication:
Spironolactone, Aldactone, Aldactazide, Aldactazine, Aldazida, Aldazide, Aldozone, Alexan, Alizar, Carpiaton, Espirone, Espironolactona, Expal, Kespirona, Lanx, Letonal, Osiren, Osyrol, Practon, Prilactone, Spiractin, Spiresis, Spirix, Spiroctan, Spirolang, Spirolon, Spiron, Spirono, Spironolacton, Spironolactona, Spironolakton, Spironolattone, Spirotone, Verospiron, Xenalon,

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Amoxinsol, Dolocordralan, Ribavirin, Rebetron, Reloxyl, Alpertan, Fenalgic, Almazine, Visacor, Amolin, Dulot, Lamal, Mafena, Esam, Trimoxsul, Venlafaxina, Zomepral, Oleptro, Irovel, Tavex, Augmentin, Metryl, Epitol, Desval, Lostam, Amoxicilina, Bromed, Prevencor, Lextor, Sulbacin, Naxopren, Ivermectin, Ivexterm, Mavicam, Klamoxyl, Arcolane, Mutabon, Lozar, Bactiver,

Alexan is used to treat certain patients with hyperaldosteronism (the body produces too much aldosterone, a naturally occurring hormone); low potassium levels; heart failure; and in patients with edema (fluid retention) caused by various conditions, including liver, or kidney disease. It is also used alone or with other medications to treat high blood pressure. Alexan is in a class of medications called aldosterone receptor antagonists. It causes the kidneys to eliminate unneeded water and sodium from the body into the urine but reduces the loss of potassium from the body.

High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

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In case of sentinel bleeding, pseudoaneurysms can be detected by computed tomography scan and treated by embolization. The stabilization and conformational changes induced by protonation are also analyzed for the natural as well as the mismatched base pair. The article reviews some recent developments in studying DNA sequence-dependent deformability, with emphasis on computer modeling. although new mothers are aware of the benefits of breastfeeding, many of them stop breastfeeding early in the postpartum period.

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Food advertising was assessed according to 7 food categories--cereal, snacks, sweets, beverages, fast food restaurants, non-fast food restaurants, and other food products--and then examined across more detailed categories. Attitudes of preclinical medical students towards caring for chronically ill and dying patients: does palliative care teaching make a difference? We searched for relationships between VEGF and VE-cadherin levels in preoperative sera of patients with colorectal cancer (CRC). The indices of certain endocrine functions in patients with benign tumors

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Reduced expression of mitochondrial electron transport chain proteins from hibernating hearts relative to ischemic preconditioned hearts in the second window of protection. Homeobox A9 transcriptionally regulates the EphB4 receptor to modulate endothelial cell migration and tube formation. A Left-Sided Approach for Resection of Hepatic Caudate Lobe Hemangioma: Two Case Reports and a Literature Review.

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Computerized tomography and an echogram showed the mass extending from the dome of the bladder to just beneath the rectus muscle. These studies in ovariectomized monkeys revealed that coronary vasospasm can be stimulated without preexisting vascular pathology, endothelial denudation or injury. Whereas threonine-monophosphorylated Sty1 showed a limited biological activity particularly at the transcriptional level, threonine-monophosphorylated Pmk1 was able to execute most of the biological functions of the dually phosphorylated kinase. Hypotheses on the physiological role of SMR1-derived peptides in male rats are discussed. PCR-based method for isolation of full-length clones and splice variants from cDNA libraries.

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Whole-body positron emission tomography with F-18 fluorodeoxyglucose for the detection of recurrence in uterine sarcomas. Orthodontic therapy can improve masticatory function in patients with malocclusion. The effects of visceral obesity and androgens on bone: trenbolone protects against loss of femoral bone mineral density and structural strength in viscerally obese and testosterone-deficient male rats. Serum obtained from gerbils after this decrease in fecundity, but before worms were expelled, was transferred passively to other infected gerbils during the peak of worm fecundity. Thus, BN is associated with substantial structural and functional alterations despite normal weight.

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To assess the efficacy of parametric imaging for the diagnosis of neovascularization in liver tumors. Paradental cysts: a role for food impaction in the pathogenesis? The products of hydrolysis by this limited action protease are quite different for the corn and Chlorella NRs. The aim of this paper is to examine cavity design for posterior resin composite restorations and to discuss various resin composite filling techniques. Quest for social accountability: experiences of a new health sciences university in Nepal.

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Operative strategies in ventrally and ventrolaterally located spinal meningiomas and review of the literature. Anomalous nonstoichiometry detected by dual label analysis of ribulose 1,5-bisphosphate carboxylase. We performed a twin study to help clarify the causes of Tojikomori and investigate the association between Tojikomori and depressive symptoms. The efficient implementation of the partial rigid-body method in parallel computation is presented, which is shown to work well in large-scale molecular dynamics simulations. We measured the changes in cutaneous bilirubin (Br) and serum Br photoisomers in two groups of 5 jaundiced newborn infants treated by intensive phototherapy (IP), one with blue light and the other with green light.

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Antigenic differences between HSV-1 and HSV-2 glycoproteins and their importance for type-specific serology. Immunosuppression and xenotransplantation of cells for cardiac repair.

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Here we report that overexpression of Je2 in CEM-C7 T-cell line is able to suppress CD95-mediated apoptosis, and apoptosis induced by TNFalpha and the glucocorticoid analogue dexamethasone, but was not able to suppress death induced by the topoisomerase II inhibitor etoposide. Treatment of cowpea seedlings with paclobutrazol, a gibberellin (GA) biosynthetic inhibitor, abolished the FR promoted epicotyl elongation, indicating a role for GAs in this process. To investigate the effect of pore size on the mechanical degradation of DNA, column permeability and enzyme biological activity, methacrylate monoliths with different pore sizes were tested.

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However, using standard HRP histochemistry we found that the capsular tissue and ligament synovia disintegrated during the incubation reaction. Asked to give a brief outline of the study, Stanley noted that a single booster dose of tetanus toxoid was given to HIV-infected and uninfected volunteers in order to stimulate their immune system. The aim of this investigation was to identify whether the type of secondary task (motor or cognitive) determined the severity of dual task interference. In this review, we provide an overview on the participation of sphingolipids and enzymes responsible for their metabolism in mechanisms underlying psychiatric disorders. Therefore, ras oncogene-transformed and nontransformed cell populations differ in their response to Ara-C.

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Analytical methods were developed for the measurement of sarin (GB) and soman (GD) at ppb levels that involved preconcentration of relatively large volumes (40-150 microliters) of a chloroform extract onto a sorbent cartridge, followed by thermal desorption and analysis by GC-flame photometric detection. Community knowledge, attitudes and practices towards tuberculosis and its treatment in Mpwapwa district, central Tanzania.

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We investigated this relationship using an instrumental variables model (IVM), a quasi-randomization technique for drawing causal inferences. Smear-layer free dentin particles which have not been exposed to heat by grinding can be obtained by room temperature high-pressure fragmentation. Effect of exercise on placental blood flow in pregnancies complicated by hypertension, diabetes or intrahepatic cholestasis. Participants were asked to report illnesses they experienced in the past 14 days.

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In this study, the catalytic activities and substrate specificities of the viral protease were examined in vitro by using synthetic peptides (11-15 residues) corresponding to the cleavage sites of the norovirus polyprotein. Different phenotypes in identical twins with cerebrotendinous xanthomatosis: case series. In a dual immunoconjugate therapy protocol, PF1/D-DAVLBHYD and PF1/B-DAVLBHYD had additive antitumor effects which were consistent with their complementary tumor reactivity. CHEDUR as well as the other products formed in control reactions are characterized extensively. All fractures repaired by this method healed with no postoperative complications.

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New technologies provide an opportunity in the way safety information is collected, helping generate new knowledge for safety profile of drugs as well as unique insights into the evolving pharmacovigilance system in general. Interactions between Aurora B and polar microtubule plus ends lead to failure in cytokinesis and abnormal midbody structure.

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To compare the effectiveness of pharmacist medication review, with or without pharmacist prescribing, with standard care, for patients with chronic pain. The inclusion criteria were as follows: final diagnosis of SPA affecting the parotid gland and articles published in Spanish or English.

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The RAPD-PCR is a potentially useful assay for the rapid characterization of neonatal infections associated with group B streptococci. DUC embryos should be deselected for D3 transfers, but should be culture to blastocyst stage for possible ET. Hereditary angioedema (HAE) is a rare, autosomal-dominant disorder caused by C1 inhibitor gene mutation. Over one hundred genes have been characterised, including the classical class I and class I-related genes, as well as the class II gene families.

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Comparison of Two Different Enteral Nutrition Protocol in Critically Ill Patients. Expression of NtAAA1 in leaves of NtARF transgenic plants attenuated lesion and suppressed pathogen resistance.

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We study the game of Dots-and-Boxes from a statistical point of view. The influence of post-rewarming temperature management on post-rewarming fever development after cardiac arrest. The correlation of periodontal disease status with systemic bone mineral density (BMD) was evaluated by dual-energy X-ray absorptiometry. Compact and lightweight support platform with electromagnetic disturbance elimination for interferometer on reversed field pinch Keda Torus eXperiment.

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In this work, we carried out the surveillance of the main coral reef of the Ecuadorian Pacific with a focus on the two most abundant and cosmopolitan species of this ecosystem, Leptogorgia sp. Pathology is not immune to the power of the media to create concern about accuracy of diagnosis in surgical pathology and cytopathology.

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A prospective study was conceived to assess the diagnostic accuracy of MEPs in comparison with digital subtraction angiography. baumannii strains harboring armA from hospitalized patients in Nepal. The fact that we observed arthritic changes in only 1 of 8 cases suggests that carpal stability obtained by this procedure is probably sufficient to obtain good functional long-term results. Less-experienced surgeons attempting complicated procedures significantly increase the risk of conversion.

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We identify a ubiquitin interaction motif at the amino-terminus of Jarid2, and demonstrate that this domain facilitates PRC2 localization to H2AK119u1 both in vivo and in vitro. The name lipometrin for lipids whose physiological activity varies with length is proposed, among these, substances active in the pea bioassay could be termed oleanimins. This report summarizes the current consensus concerning functional disorders in infants and toddlers.

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The fact that several SULTs show particular high expression in fetal tissues suggests that this activation pathway may also tamoxifen drug interaction play a role in the teratogenic effects observed. Five scenarios developed for this study were shown to be valid when using the faculty criteria for expected performance level.

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The results of this study show that DNA can be efficiently extracted from PETs archived for more than 20 years, and that large scale population studies based on PCR amplification of short target sequences are feasible. Our techniques, working together, can effectively recover complicated motion and deformation as well as the change of intensity surfaces from pairs of images in a microscopic image sequence, and has low time complexity, particularly desirable by many biological applications where large amount of DNA need to be processed. Our alternative explanation emphasizes the interaction between the reward system that regulates the liking and wanting of food oxcarbazepine suspension usp monograph modernization and the role of self-control, which is involved in maintaining the best outcome in the long run. Determinants of serum HDL-C level in a Tehran urban population: the Tehran Lipid and Glucose Study.

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In eukaryotes, most RNAs are transcribed, processed and zolin baby name meaning assembled with proteins in the nucleus and then either function in the cytoplasm or also undergo a cytoplasmic phase in their biogenesis. In addition to the synthetic compounds, the discovery of antagonists from natural origin has added a great value to this field.

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A High-Throughput Screening Strategy for Development prandin 2 mg side effects of RNF8-Ubc13 Protein-Protein Interaction Inhibitors. These results suggest that changes in the concentration of certain endogenous GAs may be involved in xylogenesis mediated by IAA plus kinetin in lettuce pith cultures. Alcoholic men and old women had a significantly lower degree of atherosclerosis in the coronary arteries, while the opposite was found in young women. Electrical foot stimulation and implications for the prevention of venous thromboembolic disease. Morphophysiological characteristics of adrenal glands in the white rat under the conditions of chronic administration of strontium 90

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Mortality and morbidity of toxic alcohols are high if prompt diagnosis and treatment are not initiated rapidly. Presentation and treatment is astepro safe during pregnancy data on 6 patients with this pathology are reviewed. Human death effector domain-associated factor interacts with the viral apoptosis agonist Apoptin and exerts tumor-preferential cell killing.