Ezetimibe and Caduet combination is used together with a proper diet to treat high cholesterol and triglyceride (fats) levels in the blood. This medicine may help prevent medical problems (eg, heart attack, stroke) caused by clogged blood vessels. It is also used to treat a condition called homozygous familial hypercholesterolemia (HoFH).

Ezetimibe is a cholesterol absorption inhibitor and Caduet is an HMG-CoA reductase inhibitor, or statin. These medicines will reduce the absorption of cholesterol from foods and the production of cholesterol in your body.

This medicine was available only with your doctor's prescription.

The Caduet/ezetimibe combination (Liptruzet(R)) was withdrawn from the United States market on June 2, 2015.

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Allelic variation in the human prodynorphin gene promoter and schizophrenia. Purification and characterization of depressor component of Agkistrodon acutus venom

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In Taiwan, an area with a very low incidence of cystic fibrosis (CF), we first screened for the most common mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene and looked for clinical correlations in 27 patients with clinically diagnosed congenital bilateral absence of the vas deferens (CBAVD). Outcomes are reported for patients who participated in an institutional review board-approved standardized questionnaire and chart review.

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Motion tracking in MR-guided liver therapy by using navigator echoes and projection profile matching. The role of structural adjustment programs in territorial mobility was debated, with some suggesting that it aggravated preexisting tendencies rather than creating them. Transcription factors: potential roles in drug-induced neuroplasticity. Preterm delivery in primiparous women at low risk: could epidemic chlamydia contribute to rise in preterm births? The absence of TIR-type resistance gene analogues in the sugar beet (Beta vulgaris L.) genome.

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Relationship of Speed, Agility, Neuromuscular Power, and Selected Anthropometrical Variables and Performance Results of Male and Female Junior Tennis Players. Macrophages infected with cytopathic bovine viral diarrhea virus release a factor(s) capable of priming uninfected macrophages for activation-induced apoptosis. Thyroid diseases have an anesthetic implication that includes difficult airway management, uncontrolled hyperthyroidism, hypothyroidism and postthyroidectomy complications. Prevalence and various clinical factors associated with cholelithiasis were studied in 199 patients who were undergoing bariatric surgery for obesity. Once genetics are taken into account, irritability in middle childhood may be particularly vulnerable to negative parenting, suggesting support for its malleability to parent-based intervention.

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Not all antibiotics tested were able to prevent intracellular replication of S. An action spectrum study showed maximum injury at 350 to 450 nanometers, with lesser activity between 450 and 700 nanometers. Microscopic Mechanism of Doping-Induced Kinetically Constrained Crystallization in Phase-Change Materials. The production of G-CSF by the kidney after ischemia-reperfusion provides a means of communication from the injured kidney to the bone marrow.

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The duration of insertion was measured from the time the device was first grasped until a normal capnography recording was obtained. When performed in prostate cancer patients, PLND should be extended, as it is a more accurate staging tool and may provide therapeutic benefit to some patients. New players for advanced prostate cancer and the rationalisation of insulin-sensitising medication.

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Central vestibular syndromes of vascular origin: vertebral artery syndrome The survey was carried out using a standardized questionnaire mailed to a representative stratified sample of 1200 physicians. Validated indicators allow quantification of realisable outcome benefits if all hospitals achieved best performer levels. Two groups of 30 normal subjects each were used as controls for the acromegalic and growth hormone-deficient patients, respectively. Light-induced dynamics of energy storage by PSI-cyclic electron flow were evident, demonstrating regulation under changing environmental conditions.

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Furthermore, a simplification of the plan, a rational staff assignment and reduced process times were accomplished. We demonstrate herein that Nurr1 newborn knockout mice have a severely disturbed breathing pattern characterized by hypoventilation, numerous apnoeas and failure to increase breathing when challenged with hypoxia. The membrane-type matrix metalloproteinases (MT-MMPs) constitute a newly discovered family of four enzymes within the matrix metalloproteinase (MMP) superfamily.

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The metabolism, excretion, and toxicity of retene and phenanthrene were examined in juvenile and larval rainbow trout during coexposure to the model CYP1A inducer beta-naphthoflavone (betaNF), or to the inducer-inhibitor piperonyl butoxide to determine if modulating CYP1A activity affected PAH metabolism and toxicity. When there is no escape: the effects of natural enemies on native, invasive, and noninvasive plants. Although in immature parasites the network is completely solubilized by detergent, the network in mature parasites is entirely detergent-resistant.

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Metallothionein contents in selected tissues of cattle from copper-deficient areas in north-east Poland. The aim of this study was to assess the association between ADAMTS13-specific CICs and ADAMTS13-related measurements, clinical and laboratory markers of disease severity, and occurrence of TTP relapse, in autoimmune TTP patients. Men and women simultaneously exposed to high levels of work stress and family demands are at high risk of experiencing mental health problems, particularly depression.

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Mac-2 BP, also known as 90K, is a highly glycosylated, secreted protein extensively studied in human cancer, which binds galectin-1, galectin-3 and galectin-7. Mice infected with the coronavirus mouse hepatitis virus, strain JHM (JHM) develop a disease that shares many histological characteristics with multiple sclerosis. p53 stabilization and transactivation by a von Hippel-Lindau protein. a decreasing Cd accumulation at a low level of Cd and probably an induction of metallothionein (MT)-like protein at a high level of Cd. Foci of hyperplastic type II pneumocytes measuring up to 4 mm were widely scattered through the lungs.

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Mobilization and utilization of cyanogenic glycosides: the linustatin pathway. Navicular index for differentiation of flatfoot from normal foot. Factors influencing the risk of clinical events during races were different for each discipline. Morbidity and mortality caused by hyaline membrane disease in a neonatal intensive care unit

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Storage and maintaining activity of ribulose bisphosphate carboxylase/oxygenase. In vivo labeling indicates that GAPC and ADH are not heat shock proteins. It seems that total hip arthroplasty does not affect the reliability of spinopelvic sagittal alignment measurements. Neoadjuvant chemotherapy for resectable advanced esophageal squamous cell carcinoma (ESCC) requires reassessment.

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Western blots with hyperimmune rabbit sera and convalescent-phase swine sera revealed antigenic variation among serotypes of T. However, the transcripts and the translated products of the genes were not found in the embryos of dry seeds. We present a hitherto unknown mechanism of how temperature-induced changes in neural networks are compensated by changing their neuromodulatory state: activation of neuromodulatory pathways establishes a dynamic coregulation of synaptic and intrinsic conductances with opposing effects on neuronal activity when temperature changes, hence rescuing neuronal activity.

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Expectancies Mediate the Relations Among Pain Catastrophizing, Fear of Movement, and Return to Work Outcomes After Whiplash Injury. Retrieval, monitoring, and control processes: a 7 tesla FMRI approach to memory accuracy. To assess the current attitudes, beliefs, and practice patterns among vitreoretinal surgeons when dealing with symptomatic floaters in patients with otherwise healthy eyes.

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In this study, magnetofection was investigated in airway epithelial cell models mimicking extracellular and cellular barriers. Among our patients, its occurrence was predominantly associated with an increased venous pulsatility index due to tricuspid regurgitation or venous outflow obstruction.

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This method is applied to identification of the products obtained upon ion-exchange purification of synthetic 2-carboxyarabinitol 1-P. The circumference and the shape of the leg were measured and recorded. Phase-slip lines can be viewed as dynamically created Josephson junctions in a homogeneous superconducting film.

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Prevalence of anaemia in semi-urban areas of Peshawar, Pakistan: a challenge for health professionals and policy makers. Significant UWW and LECH increases were detected at 24 hrs after a single dose of 100 microg/kg TAM. Socialization of coping with community violence: influences of caregiver coaching, modeling, and family context. Exposure to anticholinergic and sedative drugs was thoroughly ascertained, though the specific calculation of the DBI differed across studies. Quantitative discrimination of ANF receptor subtypes in portal hypertension.

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The retreat of death: the epidemiological transition in Germany during the nineteenth and twentieth centuries It inhibited stolon elongation, and caused thickening and diageotropical growth of the stolon. Our results suggested that perinatal brain masculinization requires AR function and that expression of male-typical behaviors in adults is mediated by both AR-dependent and -independent androgen signaling. Dynamic and functional characteristics of the phagosomal membrane

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Clinical evaluation and morbidity of 201 free jejunal transfers for oesophagopharyngeal reconstruction during the 20 years 1984-2003. Focus groups and cognitive interviews are now a standard part of the development of valid and reliable survey instruments. The two procedures are equally safe and effective with regard to pain relief, but OPPHR is superior to PPPD not only in the operation data and morbidity, but also in the quality of life 1 year postoperatively. Crassulacean acid metabolism (CAM) is a physiological adaptation of plants that live in stress environment conditions.

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Prospective food diaries demonstrate breastfeeding characteristics in a UK birth cohort. Results indicate widespread readership and prescription of popularized self-help books among psychologists and a positive evaluation of their utility. Finally, we observed that preconditioning of human macrophages by LXR agonist treatment increased the release of arachidonate-derived eicosanoids, such as prostaglandin E2 and thromboxane after lipopolysaccharide stimulation, with a significant attenuation by LPCAT3 silencing. Priming stimulation of basal but not lateral amygdala affects long-term potentiation in the rat dentate gyrus in vivo.

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A novel mitochondrial intergenic spacer reflecting population structure of Pacific oyster. Visualizing the behavior of human Rad51 at the single-molecule level.

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A pharmacological analysis of liver secretory function under altered microsomal enzyme activity Health and Economic Impact of Switching from a 4-Valent to a 9-Valent HPV Vaccination Program in the United States. A comparative study of commercial liquid chromatographic detectors for the analysis of underivatized amino acids. Both cellular and humoral immune responses are crucial to induce potent anti-tumor immunity, but most of currently conducted peptide-based cancer vaccines paid attention to cellular responses alone, and none of them are yet approved as a therapeutic modality against cancer patients.

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Major complications include coronary ostial stenosis or embolism in an epicardial coronary artery. Cytochrome and alternative pathway respiration in green algae : measurements using inhibitors and o(2) discrimination. In order to exclude any olfactory stimulation, the inhalation of the fragrances was prevented by breathing masks.

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This study looked at the prevalence and variables associated with hospice caregiver depression and anxiety, as well as the relationship between the two conditions. The influence of low temperature on the structure and function of the photosynthetic apparatus was investigated in Phaseolus vulgaris L. The time course of the plasma concentrations of isoniazid, rifampin, and pyrazinamide was assessed in a group of 13 patients with lung tuberculosis treated over a period of 2 months on a continuous daily basis with a fixed triple combination of the same drugs. The vascular endothelial cells and the few granulocytes did not express PINCH in these rabbits.

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Studies on the development of a MT inducer will encourage potential clinical use for obesity- related diseases. An examination of the literature on animal and human studies of drugs on eating behavior, food intake, and body weight leads to the conclusion that the models used, at present, do not truly represent the complexity of the processes being investigated. The aim of this study was to investigate the effects of different combinations of bronchodilator therapies on airway inflammation in COPD. KM-2 recognized apoptosis-induced acetylation of H4 at lysines 8, 12, and 16.

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As a consequence, the correct specific surface areas of the adsorbents cannot be calculated. The defect was left empty, sutured with a 5-0 suture or filled with a hyaluronan/collagen composite matrix without cells, with platelet rich plasma or with autologous mesenchymal stem cells. This article reviews the current understanding of different MSC populations in orofacial tissue compared with those derived from bone marrow. Several neuronal cell populations were intensely labeled with the ANX6 monoclonal antibody (MAb), including layer 5 of neocortex, the lateral septum, the lateral hypothalamic area, the red nucleus, and the Purkinje cell layer in cerebellum.

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Apoptosis is a universal cellular defense mechanism against viral infection. The influence of aging on the regeneration of ascorbic acid from dehydroascorbic acid was investigated as a possible cause of declining ascorbate concentrations. trachomatis pathogroups, was explained by the incorporation of genetic fragments unique to the ocular and/or urogenital strains into the LGV- and urogential strains in addition to the genome-wide SNP AT content differences between the three pathogroups. Maternal mosaicism for a novel interleukin-2 receptor gamma-chain mutation causing X-linked severe combined immunodeficiency in a Navajo kindred. Neuroimaging studies of temporal processing suggest that subsecond and suprasecond intervals could be mediated by distinct neural substrates.

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The implications of these findings and directions for further research are discussed. Here, we use ANNs to derive encoding schemes for the amino acid types from protein three-dimensional structure alignments. Understanding downstream outcomes in clinical practice should better inform individualized decisions among older men considering PSA screening. Recurrent Early Thrombus Formation in HeartMate II Left Ventricular Assist Device. Affected by mid-concentration of ACP and PDGF-BB, c-sis mRNA expressed was down-regulated.

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Up to the present day, pain management in the ICU (Intensive Care Units) is a unresolved clinical problem due to patient heterogeneity with complex variation in etiopathology and treatment of the underlying diseases. Surgery along with adjuvant radiotherapy was used for complete cure. The role of platelets and ADP in experimental thrombosis induced by venous stasis in the rat. We searched MEDLINE and EMBASE from 1966 to 1999, the Cochrane Controlled Register, citations of relevant articles, and proceedings of international meetings for eligible randomized controlled trials. Simvastatin and vitamin E effects on cardiac and hepatic oxidative stress in rats fed on high fat diet.

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Borderline personality disorder (BPD) is characterized by emotional instability, interpersonal dysfunction, and other features that typically develop before a background of insecure attachment and traumatic experiences. When discs cultured in the dark were transferred to light, most dumbbell-shaped chloroplasts separated into daughter chloroplasts in less than an hour. Recognition of the importance of ER stress and UPR signalling pathways in normal and dysregulated immune responses has greatly increased in the past few years. Four groups received IP 0.1, 1, and 10 mg/kg MID or an equal volume of its vehicle benzyl alcohol 0.1 mg in 1 ml saline, while the other three groups received IT 10 and 100 micrograms MID or 0.5 microgram benzyl alcohol in 5 microliter saline. The lack of clear protection in these studies may be due to the failure of the various immunizing regimes to induce an antibody response prior to challenge.

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Photoionization of laser-cooled atoms can produce electrons of intrinsically high coherence, but has been too slow for ultrafast electron diffraction. Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction. Production of embryos in vitro, particularly when using an extended period of in-vitro culture, may predispose the embryo to phenomena such as the large offspring syndrome, which is likely to alter gene expression, particularly of imprinted genes.

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Three-dimensional endorectal ultrasound using a new freehand software program: results in 35 patients with rectal cancer. This review will highlight our current knowledge of the roles of sumoylation in regulating NF-kappaB signaling and functions and will address future perspectives.

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Racial disparity in all-cause mortality among hepatitis C virus-infected individuals in a general US population, NHANES III. Psittacosis is rare among children and severe cases appear exceptional. Antisense inhibition of mdr2 mRNA expression increased diC4PC uptake induced by total liver mRNA from mouse and rat.