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Calaptin (Verapamil)

After successful treatment of the arrhythmia using Calaptin i.v., a routine echocardiographic examination showed the presence of a left atrial mass, and its appearance suggested the diagnosis of a left atrial myxoma. Compounds 1-5 were pharmacologically evaluated for their cytotoxicities against five human cancer cell lines (HCT-8, Bel-7402, BGC-823, A549, and A2780) and their reversing activity towards multi-drug resistance A549/taxol tumor cell line, and the results showed that all of the tested compounds exhibited very low cytotoxicities, while compound 4 possessed twice the reversing activity as that of Calaptin at 10 muM.

Other names for this medication:
Verapamil, Calan, Calaptin, Isoptin, Verelan,

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Farcet, Amarin, Clomipramine, Abalam, Diabose, Clindamax, Caditar, Antiplar, Medazol, Ergoset, Cavumox, Vazkor, Diseptyl, Levocin, Epitol, Lotim, Lokit, Venlaxor, Teril, Clonamox, Cozole, Normatens, Bromergon, Citara, Lomac, Ketipinor, Robaz, Tromax, Metrovax, Antilip, Neoset, Fursemid,

Calaptin is used with or without other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Calaptin is called a calcium channel blocker. It works by relaxing blood vessels so blood can flow more easily. It may also lower the heart rate. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This drug may also be used to treat other heart diseases (such as hypertrophic cardiomyopathy, fast/irregular heartbeats) and to prevent chest pain (angina).

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The results from early clinical trials (Phase I and II) are encouraging, suggesting that HIFU is a promising treatment for small breast cancer. Brassinolide, a plant sterol from pollen of Brassica napus L., induces apoptosis in human prostate cancer PC-3 cells. This formulation appears to be clinically acceptable and provides a convenient dosage form for use in pediatric patients.

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Subarachnoid hemorrhage and transient global cerebral ischemia result in similar pathophysiological changes in the cerebral microcirculation. Effect of acute global ischemia on the upper limit of vulnerability: a simulation study. Scatchard plot analysis revealed a significant decrease in both K(d) and B(max) for dopamine D2 receptors. Our results support the notion that Herp2 functions as a critical switch downstream of Notch and BMP receptor signaling pathways in ECs.

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Several groups have reported that determinants of target-mediated elimination could include mAb-target binding, target expression, and target turnover. According to Aglietti criteria, 11 knees were rated as excellent, 3 good, 1 fair, and 1 poor.

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To deal with such a challenging problem, the ensemble classifier was introduced. Poorer clinician-rated engagement was associated with greater positive and negative symptoms, greater general psychopathology, and poorer premorbid social adjustment. An 80-old-year woman was diagnosed with a huge liver cyst with abdominal pain.

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Sexual dimorphism of the human stress response may be due to estradiol-mediated stimulation of hypothalamic corticotropin-releasing hormone synthesis. Superficial femoral artery occlusion: nitinol stents achieve flow and reduce the need for medications better than balloon angioplasty alone. Correlates of Healthy Lifestyle Beliefs and Behaviors in Parents of Overweight or Obese Preschool Children Before and After a Cognitive Behavioral Therapy Intervention With Text Messaging.

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Our results have demonstrated that TCE may be biodegraded to nontoxic products under certain conditions. An evidence of this ambiguity is the prevailing image of scientists in popular culture: that of the mad scientist. Post-traumatic stress disorder and HIV risk behaviors among rural American Indian/Alaska Native women. There are pitfalls associated with the use of intraoperative neuromonitoring during thyroid surgery.

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C5b-9 activates cytosolic phospholipase A(2) (cPLA(2)), and products of cPLA(2)-mediated phospholipid hydrolysis modulate GEC injury and proteinuria. Synthesis, Characterization, and Anti-Inflammatory Activities of Methyl Salicylate Derivatives Bearing Piperazine Moiety. Identifying pattern-defined regulatory islands in mammalian genomes. The immunohistochemical study of valves constructed in the colon of rats submitted to abdominoperineal amputation and perineal colostomy revealed denervation at the seromyotomy site.

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US-guided EPI eliminates the fibrotic accumulation that causes PHTrSNE, without the semimembranosus tendon or the sciatic nerve being directly involved during the procedure. Emergency physicians often use the Glasgow Coma Scale (GCS) to help guide decisions in patient care, yet the reliability of the GCS has never been tested in a typical broad sample of emergency department (ED) patients. Fetal head circumference (HC) and biparietal diameter (BPD) are highly correlated with fetal brain volume and are measured on fetal ultrasounds.

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It was in the cytoplasmic membrane as well as nuclear fractions, but not in the soluble cytoplasmic fraction of SH-SY5Y neuroblastoma cells. Soil and preen waxes influence the expression of carotenoid-based plumage coloration. Toxicologic effects of five soil nematocides in cattle and sheep.

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The objective of this study is to determine the level and factors associated with job satisfaction among Saudi and non-Saudi physicians. A robust transcortical profile scanner for generating 2-d traverses in histological sections of richly curved cortical courses.

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Can self-monitoring of foot temperature help prevent recurrence of diabetic foot ulcers? With the same timing of the initial change, genes which share similar patterns of expression for any number of sampling intervals from the beginning should be considered co-expressed at certain level(s) in the gene networks. The critical scientific gaps and future research directions in this field are discussed. To our knowledge, no previous studies have evaluated the impact of habituation to either low protein intake (LOW PRO) or high protein intake (HIGH PRO) on the postprandial muscle protein synthetic response.

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Here we describe its retrospective evaluation and the use we subsequently made of judges comments on the validation data to evaluate TraumaTIQ, a new critiquing interface for TraumAID, investigating the question of whether, with timely recording of information, a system could produce commentary in line with that of human experts. The published literature comparing EUS and CT for preoperative assessment of pancreatic cancer is heterogeneous in study design, quality, and results. Retrospective epidemiological studies show that metformin, a drug commonly used in type II diabetes, has antitumor properties.

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Here we demonstrate that the chemical composition of the substrate unexpectedly plays a significant role as well. These differences were independent of age-related changes at the choroid-retina interface.

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Subjects were classified into four groups each comprised of 30 participants: diabetic retinopathy with hypertension (DRH), diabetic retinopathy without hypertension (DR), hypertension without diabetes mellitus (H), and healthy controls without diabetes and hypertension (C). Using FoCUS to evaluate for pericardial tamponade, however, is more involved. Child toy safety: An interdisciplinary approach to unravel the microbiological hazard posed by soap bubbles.

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Synergistic effect in combination with tissue factor pathway inhibitor. Autoclaving at 2.56atm, for 30min, produces a significant decrease of IgE-binding capacity of peanut allergens. The implications of these results for rational ligand design are discussed. naledi, thus providing further evidence of locomotor diversity within both the hominin clade and the genus Homo. We propose that future studies should examine the possibility that associated disorders arise from a defect within the monocyte-macrophage system, perhaps secondary to ceroid accumulation.

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One-Step Multipurpose Surface Functionalization by Adhesive Catecholamine. Molecular cloning and characterization of six genes, determination of gene order and intergenic sequences and leader sequence of mumps virus.

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As there are few studies on the cranial anatomy of this species, we aimed to describe the cranial myology to contribute to the anatomical knowledge of this species and to make some assumptions about functional anatomy. Several methods are available to help you show that your therapy is effective, even when it is not.

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This method shows a broad substrate scope, including not only aryl azides, but also unactivated benzyl and alkyl azides. One of these RNAs, myosin heavy chain, is critical in presynaptic sensory neurons for the establishment of long-term facilitation, but not for its persistence. Significance of ST-segment morphology noted on electrocardiography during the recovery phase after exercise in patients with ischemic heart disease as analyzed with simultaneous dual-isotope single photon emission tomography.

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Expression of ABCG2 in intestinal mucosa was measured with real time polymerase chain reaction (PCR). Identification of G alpha s messenger ribonucleic acid splice variants in human granulosa cells. Medline, the Cochrane Effective Practice and Organisation of Care (EPOC) database (from inception to July 2010) and references of included studies. The materials were derived from mesoporous aluminosilica-surfactant mesophases via benign template removal methods, which allowed the retention of molecular ordering in surfactant-free materials. Functionally, the glycoprotein can adhere to and stimulate the thymidine incorporation of human mononuclear cells (MNC) in modest degree via its membranotropic property.

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However, the molecular nature of the closed and open states of syntaxin is not well defined. Imaging can be conditionally performed in carefully selected subjects after collection of substantial safety information and evaluation of the detailed exposure scenario (RF coil/type and position of implant). Adolescents between the ages of 10 and 19 are exposed to a series of substances capable of causing contact dermatitis.

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Atrial fibrillation is the most common clinical arrhythmia, affecting millions of people worldwide and utilizing billions of dollars annually in heath care costs associated with the disease. Transfection of the p73 gene into neuroblastoma cells that lack detectable p73 protein has been shown to result in growth suppression and to induce neuronal differentiation.

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Fabrication of GM3-enriched sphingomyelin/cholesterol solid-supported lipid membranes on Au/SiO2 plasmonic substrates. Inhibition of collagen-induced platelet reactivity by DGEA peptide.

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The reaction time courses are complex at all the wavelengths studied. Surgical treatment of the implants was performed at the second laparoscopy. Ocular hemodynamics become abnormal during the early stage of DRP and worsen with the progress of DRP. Transesophageal echocardiography is the method of choice for investigating suspected intracardiac masses. This report details the surgical treatment of 44 patients with aneurysms of the vertebral and basilar arteries.

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However, postoperative pathological evaluations revealed components of CD10-positive and CD10-negative lymphoma cells within the lymphoma lesion. Patients should be informed that severe neutropenic infection without fever can occasionally occur during cancer treatment with chemotherapy. Leukocytes are found within the testis of most, if not all, mammals and are involved in immunological surveillance, physiological regulation and tissue remodelling.

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Two acidic residues (D259 and E264) were candidates for maintaining H296 in the protonated state and their roles were examined by mutagenesis. This study aimed at investigating the production of reactive oxygen specie during the inflammatory response in patients with sepsis. Lupus band test still has no clearly defined position within either diagnostic or disease activity measuring tools for systemic lupus erythematosus (SLE).

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The assay is applied to estimation of nitrogenase in nodulated legume roots by measuring the ethylene produced from acetylene. Analysis revealed that one WRI item related to Personal Causation and three items related to Roles and Habits were supportive factors for successfully returning to employment among soldiers that were working or engaged in returning to work.

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Recurrent abdominal and pelvic abscesses: incidence, results of repeated percutaneous drainage, and underlying causes in 956 drainages. On the problem of the method of rheographic examination and the normal rheogram of the liver in children How miRNA localizations and functions are regulated by protein modifications on the core miRNA-binding protein Argonaute (AGO) during normal and stress conditions will be explored, and in conclusion new AGO partners, non-AGO miRNA-binding proteins, and the emergent understanding of miRNAs found in the nucleoplasm, nucleoli, and mitochondria will be discussed.

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In an attempt to identify the binding site for SPARC on VEGF, we hypothesized that this binding site could overlap at least partially the binding site of VEGF receptor 1 (VEGFR-1), as SPARC acts by preventing VEGF-induced phosphorylation of VEGFR-1. The pro-apoptotic and anti-apoptotic BCL-2 proteins function through protein-protein interactions in soluble and membrane-associated states.

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To establish whether a relationship exists between computed tomography features of lung opacities in severely neutropenic patients and their Aspergillus or bacterial etiology. Clinical studies are ongoing with respect to early diagnosis of breast cancer and arthritis. The early introduction of combination therapy of high-dose corticosteroid and nucleoside analogue is beneficial for the rescue of severe acute exacerbation of chronic hepatitis B. Thirty-four patients discontinued participation due to treatment-related nonserious adverse events.

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Sparse transient microtubule populations can be detected between pericentriolar regions and surface sites while microtubule assembly advances. Irregular channels with several vesicles occur between the cytoplasm and BM.

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Increased levels of C-reactive protein (CRP) could be detected in subjects with acute coronary syndrome (ACS). Hyperhidrosis is thought to result from a functional impairment of the sympathic nervous system. The intervertebral disks of progressive ankylosis mice were examined at successive periods in order to describe the pathologic lesions involved and to explore possible relationships with any known human disorder. Post-infarction, however, scar tissue formation impedes the efficacy of device-based therapy.

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GLP-1 is a hormone secreted by L-cells of distal small intestine and colon. Subjective well-being is by far the domain least affected by chronic medical conditions, while physical functioning and health perceptions are most affected. Quantitative assessment of the effectiveness of phase 1 orthodontic treatment using the American Board of Orthodontics Discrepancy Index. Documenting and displaying words to remember someone in death reaffirms their life. Monitoring ground-level air for trace analysis: methods and results.

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A global comparability approach for biosimilar monoclonal antibodies using LC-tandem MS based proteomics. The aim of this study was to determine the safety and efficacy of ultrasound-guided IJV CVP placement in elderly oncologic patients.

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Studies of chromatographic behavior were complemented by torvacard 20 mg cenacolo solid state NMR experiments which provided valuable information regarding the relationship between stationary phase solvation and selectivity. A total of 96 clinical isolates of CoNS were characterized and subjected to biofilm detection by tissue culture plate method (TCP), tube method (TM), congo red agar method (CRA) and PCR.

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Whereas the rostrodorsomedial prefrontal cortex was smaller in structure and function in both disorders, this was concomitant with increased structure and function in BG and insula in OCD patients, but a reduction in ASD patients, presumably reflecting a disorder-specific frontostriatoinsular dysregulation in OCD in the form of poor frontal cambia formato immagine online game control over overactive BG, and a frontostriatoinsular maldevelopment in ASD with reduced structure and function in this network. Fluctuations of light, temperature, and changing concentrations of the various reducible substrates pose unique regulatory problems to photoautotrophic plant cells. A case of acute drug-induced hemolytic anemia associated with glucoso-6-phosphate dehydrogenase deficiency

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Safety and efficacy of tenecteplase versus alteplase in acute coronary syndrome: a systematic review and meta-analysis of randomized trials. At the spatial scale in this study, the biogeography of MTB is relatively more influenced by environmental factors than geographic distance, suggesting that local conditions override the effects of dispersal history on structuring MTB community. In order to lansoprazole domperidone capsules better probe SynCAM function in neurons, we produced a fusion protein between the extracellular domain of SynCAM1 and the constant fragment of human IgG (SynCAM-Fc).

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To understand the variation in scoliosis surgery and perioperative care among spinal deformity surgeons. PLAN conducted an ethnographic study which revealed that pneumonia does not translate well taking citalopram and smoking weed into Aymara, and other less serious folk illnesses have similar symptoms.

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thaliana background: either by affecting internode elongation (IscLFY1) or by causing homeotic conversion of shoots into flowers (IscLFY2). In absence of granuloma or lepra bacilli, other morphologic changes in endoneurium and perineurium can be of help in making a probable diagnosis of PNL and treating the patient with polprazol 40 mg cena vs lesnar multidrug therapy. The presence, reactivity, adsorption of gas and ions, proteins, DNA, cells and tissues on graphene have been successfully monitored with graphene.

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The mechanism of action is unclear, but appears to be consistent with the lowering of autoantibody levels, where relevant antibodies are quantifiable. In patients with hypertension, inhibition of Rho-kinase has been shown to decrease the increased vascular resistance. These results indicate that different regions of mouse CD14 are required losartan brand name or generic for TLR4- and TLR2-mediated activation of NF-kappaB and suggest that amino acids 35-44, 151-153, 235-243, and 273-275 of mouse CD14 play an important role in LPS binding and its transfer to TLR4/MD-2. Comparison of measures for prospective identification of venous stenoses. Physicians without appropriate training in diving medicine may inform a diver they are safe to continue diving with their condition without appreciating the potential risks.