Acema is a strong painkiller. It's used to treat moderate to severe pain, for example after an operation or a serious injury.

It's also used to treat long-standing pain when weaker painkillers no longer work.

Acema is available only on prescription. It comes as tablets, capsules and liquid drops that you swallow. It can also be given by injection but this is usually only done in hospital.

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On-line monitoring system of P5CDF homologues in waste incineration plants using VUV-SPI-IT-TOFMS. Scope and limitations of iodothyronine deiodinases in hypothyroidism. Effects of type of dietary fat on indices of immune status of rabbits. Furthermore, the transduced cells were found to maintain the level of EGFP expression in vivo for at least 15 days. Type XIII collagen (ColXIII) is a transmembrane protein thought to be involved in cell-cell and cell-matrix interactions.

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Ketamine was then put on the mature urothelium using paper or agarose vectors for 48 hours. The molecular weight of protein of the gastropod sample ranged from 2-110 kDa on SDS-PAGE. Despite recent advances in medical technology, monitoring of asthma and COPD has not changed significantly.

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Waist circumference as the best predictor of noninsulin dependent diabetes mellitus (NIDDM) compared to body mass index, waist/hip ratio and other anthropometric measurements in Mexican Americans--a 7-year prospective study. EPR allowed observation of NO-induced transformation of the paramagnetic trap, NN., to the corresponding iminonitroxide, IN. Sudden cardiac death during exercise due to an isolated multiple anomaly of the left coronary artery in a 12-year-old girl: clinicopathologic findings. Therefore, it is important to begin with treatment in the early phase of the disease.

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AdHO-1-mediated gene transfer into aorta endothelial cells (ECs) or CO delivery resulted in a significant reduction in intimal thickness compared to untreated or noncoding adenovirus-treated controls. We also show that Hck interacts with Yes associated protein (YAP), a transcriptional co-activator of p73, and shRNA mediated knockdown of YAP protein reduces p73 induced Ipaf promoter activation.

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Retention Mechanism for Ion-Pair Chromatography with Chaotropic Reagents. Together, our findings reveal a new previously unsuspected role of TLR7 in the generation of D-series SPMs and the resolution of allergic airway inflammation. Subjects were 58 normotensive, healthy black men age 23 to 47 years. Literature on in vivo microdialysis studies measuring extracellular 5-HT and 5-HIAA has been analysed with special attention to the great importance of the 5-HT re-uptake mechanism in determining their extracellular concentrations.

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pylori infection was achieved using the carbon urea breath test (14C-UBT). Persistence of bactericidal antibodies following booster vaccination with 4CMenB at 12, 18 or 24months and immunogenicity of a fifth dose administered at 4years of age-a phase 3 extension to a randomised controlled trial. The findings provide support for the hypothesis that lower mortality among individuals with CVD and overweight/obesity is a product of biases involving reverse causation and confounding by smoking. A report of a worker suffering from pneumatosis cystoides intestinalis following trichloroethylene exposure. Determination of hydroxyl radical photoproduction rates in natural waters.

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Visual and pursuit-related activity in extrastriate areas MT and MST. However, qualitative and quantitative changes in saliva and oral microbiota, presence of oral mucositis and radiation-related caries are expected, as they represent the well-known side effects of treatment with ionizing radiation.

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HIV-1 Transmitted Drug Resistance Mutations in Newly Diagnosed Antiretroviral-Naive Patients in Turkey. Assays of several marker enzymes showed that the final mitochondrial preparations obtained are nearly free from other contaminating organelles, e.g. The effect of EEG biofeedback on reducing postcancer cognitive impairment.

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The TRS and RS-14 were negatively correlated with depressive symptoms in company workers and psychiatric outpatients and with anxiety in psychiatric outpatients, and were positively correlated with social support in company workers. This study investigates the effects of the oxygen radical scavenger tirilazad mesylate on leukocyte-endothelial interactions, macromolecular leakage, and microhemodynamics in mesenteric venules during endotoxemia.

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The discovery of actionable driver mutations such as epidermal growth factor receptor (EGFR) and microtubule-associated protein-like 4 anaplastic lymphoma kinase (EML4-ALK) and their highly responses to EGFR and ALK tyrosine kinase inhibitors (TKIs) in patients with advanced non-small-cell lung cancer (NSCLC) allowed precise medicine into reality. When segments of such dim-light-grown leaves were exposed to 30,000 lux at either 0 degrees C or 30 degrees C, treatments with aminotriazole or haloxidine (group 1) showed no or only minor changes of their chlorophyll contents.

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We thus propose that Bsg is part of a transsynaptic complex regulating synaptic compartmentalization and strength, and coordinating plasma membrane and cortical organization. Comparison of the steady-state pharmacokinetics of topiramate and valproate in patients with epilepsy during monotherapy and concomitant therapy.

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The partial IL-8 inhibition by FP could be closely related to the anti-inflammatory activity of this corticosteroid. The quality of sequence alignment is crucial, especially in the former approaches although usual alignment methods have difficulty in STR regions due to insertions and deletions caused by the variations of repeat numbers. Distribution systems and geographic availability were determined, and purchased samples were found to be very high in lead content. Effects of vacuum suctioning and strategic drape tenting on oxygen concentration in a simulated surgical field.

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During the last decades, posttransplant donor-derived adoptive cellular immunotherapeutic strategies have been progressively developed for the treatment of graft-versus-host disease (GvHD), infectious complications, and tumor relapses. Oropharyngeal dysphagia and gross motor skills in children with cerebral palsy. Information is presented on marriages, births, and deaths in West Germany in 1988. Coerulospinal influence on recurrent inhibition of spinal motonuclei innervating antagonistic hindleg muscles of the cat.

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Here we use a new autocorrelation analysis to detect cycles in a homogenous sediment core, E602, from the northern shelf of the South China Sea. It is critical that such Internet-based information is relevant, current, balanced, and easy to access and navigate. Rainwater chemistry at the summit and southern flank of the Itatiaia massif, Southeastern Brazil. In a similar fashion, there was a concentration-dependent inhibition of neutrophil adherence to plastic and EC following stimulation with PMA (10 ng/ml), human C5a (5 micrograms/ml) or formyl-met-leu-phe (FMLP, 2 x 10(-7) M).

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A cross-sectional population-based study has been conducted in the smoking cessation services participating in the national database. Male and female rats were exposed to a free choice of oral nicotine/water for 24weeks, starting at five weeks of age.

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Synergistic drug combination effectively blocks Ebola virus infection. The concentration of IL-5 in serum was positively correlated with the number of eosinophils in peripheral blood of AR and AS.

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Although the patient received percutaneous abscess drainage and antibiotic therapy, he lost his eyesight. A questionnaire was mailed to all members of the AAGL to determine the current performance of laparoscopic-assisted vaginal hysterectomy (LAVH), and to assess the relative frequencies of techniques and complications. We describe a simple, rapid method for MIL-based plasmid DNA extraction from crude bacterial cell lysate in which DNA-enriched MIL is transferred directly to a PCR tube for analysis. Expression and mutation analysis of Tpit in the canine pituitary gland and corticotroph adenomas.

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Diacylglycerol kinase from suspension cultured plant cells : purification and properties. According to some researchers, smoking affects the mineral component of bone tissue. Our results shed light on an interdependent relationship between Alp14/TOG and Alp7.

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We have applied this strategy for the identification of the sulphation, blood group antigens and sialic acid linkages on complex N-and O-glycans released from glycoproteins. Clinical assessments were performed by a non-treating physician. When excised second leaves from 2-week-old barley (Hordeum vulgare var Larker) plants were incubated in a wilted condition, abscisic acid (ABA) levels increased to 0.6 nanomole per gram fresh weight at 4 hours then declined to about 0.3 nanomole per gram fresh weight and remained at that level until rehydrated. A large number of transgenic plants have been developed which were able to utilize sodium phytate as sole source of phosphorus.

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We report a 31-year-old man with pityriasis rubra pilaris, refractory to conventional treatments, successfully treated with ustekinumab monotherapy for over 64 weeks. We report a case of severe hypophosphatemic osteomalacia and renal Fanconi syndrome induced by low-dose ADV in a CHB-related cirrhosis patient, and discuss the case through a thorough review of other cases reported in the literature. Selection and initial characterization of partially nitrate tolerant nodulation mutants of soybean. However, it is unclear whether the modern ribosome, and in particular its large conformational changes during decoding, are the outcome of adaptation to its task as a decoder or the result of other constraints.

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In-hospital arrests were prospectively audited over a 6-year period. A proposal for a forum to develop guidelines for expert witness testimony in Pap smear cytology is discussed. In a significant number of patients, previously implanted leads cannot be removed during OHT. A quantitative method for evaluating the effects of drugs on bone marrow cellularity using the same experimental animal. The purpose of this in vitro study was to evaluate the biomechanical effects of an expanded platform-switching design for immediately loaded small diameter implants on bone strains.

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Among the most common age-associated malignancies are non-melanoma skin cancers, comprising the most common types of human cancer. Endothelins (ETs), 21-amino-acid peptides involved in the pathogenesis of various diseases, bind to ET(A) and ET(B) receptors to initiate their effects.

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In breast cancer surgery, axillary dissection is currently considered an essential step. Cytogenetic analysis was performed in 80 patients with bladder tumor. The effect of the combined administration of Diacarb and sodium bicarbonate on the elimination of uranium in various routes of its entry into the organism

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Esophageal dysmotility is a common occurence after surgical repair of proximal esophageal atresia (EA) and distal tracheoesophageal fistula (TEF). Thus, statin therapy should be considered for patients with HCV who are at risk for coronary heart disease and do not have significantly elevated serum transaminase levels at baseline.

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In view of the data presented here the balance between carboxylation and decarboxylation reactions seems to be the major factor for the observed seasonal differences. Administration of a diet high in both fat and cholesterol to ABCG1 mice results in massive cholesterol accumulation in both the liver and lungs. The enormous evolutionary and ecological success of Holometabola has been attributed to their unique postembryonic life phases in which nonreproductive and wingless larvae differ significantly in morphology and life habits from their reproductive and mostly winged adults, separated by a resting stage, the pupa. Despite unequivocally worse health, expenditure on Indigenous people through the Pharmaceutical Benefits Scheme (PBS) is considerably less than for other Australians.

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Astemizole, but not tacrolimus, prolonged the survival time of prion-infected mice. Placental transfer of cefoperazone and sulbactam in the isolated in vitro perfused human placenta. To compare the prevalence of tuberculosis infection in BCG vaccinated versus non-vaccinated school age children in a tuberculosis endemic region. This technique offers a possibility to repair the defects of two adjacent fingers.

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and A.S.) independently reviewed each report identified by the searches and recorded predetermined information relevant to the inclusion criteria. We report the case of a 26-year-old male patient with 2-week history of Brucella aortic valve endocarditis that was referred from general hospital to our hospital emergency room with pallor of the skin and mucous membranes accompanied by systemic hypotension and chest pain. Antioxidant, Antimicrobial and Cytotoxic Properties as Well as the Phenolic Content of the Extract from Hancornia speciosa Gomes. The most appropriate mathematical model of this relationship was developed by analyzing the logarithms of 30 anatomical measures and a logistic transform of the OCM percent correct score.

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However, retropeptides with oxygen replaced by the sp(2) sulfur have not exhibited such properties. Abuse liability scales were elevated for alcoholic participants above control levels after alprazolam and diazepam. The ODTF (optical density thickness function) method, which is based on a function relating grey level values of the aluminium wedge image and the corresponding thicknesses of the wedge, induced less contrast correction error than the CDF (cumulative density function) and the LSQA (least square quadratic approximation) methods. The pros and cons of neoadjuvant chemotherapy for treating breast cancer patients are reviewed.

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JSAP1 (also termed JIP3) is a scaffold protein that interacts with specific components of the JNK signaling pathway. Impaired placental mitochondria RCC functions can lead to adverse pregnancy outcomes. The first potent inhibitor of mammalian group X secreted phospholipase A2: elucidation of sites for enhanced binding. Separation and characterization of four hexose kinases from developing maize kernels.

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Knockdown of eIF5A-2 by specific siRNA exhibited the similar effects as GC7 did. Eyes with previous retinal surgery, giant retinal tear, Grade C or higher proliferative vitreoretinopathy, or less than 6 months of follow-up were excluded from the study. Analysis of Staphylococcal cassette chromosome mec in BD GeneOhm MRSA assay-negative strains.

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Whole tissue tPA mRNA increased dramatically with hyperoxia and in situ hybridization analysis showed tPA mRNA in the endothelium of the same types of vessels as antigen. In teeth of the sea urchin Lytechinus variegatus, we recorded high-resolution secondary ion mass spectrometry (SIMS) maps of Mg, Ca ,and specific amino acid fragments of mineral-related proteins including aspartic acid (Asp). The combined intervention safely reduced drug use in very old inpatients and outperformed usual geriatric care. Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are chronic cholestatic liver diseases, biochemically characterized by an elevated serum bilirubin, alkaline phosphatase and gamma-glutamyl transferase.

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The osteoporosis self-assessment tool is recommended by the authors because of its predictive power and ease of use. Between April 1994 and July 2004, 8 patients were diagnosed with NA of the urinary bladder: 3 men and 5 women, aged 23-77 years (mean 49.6).

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We identified additional, potentially contributory copy number changes in a subset of patients, including one patient each with 16p11.2 deletion and 15q13.3 deletion. Mitochondrial replacement approaches: challenges for clinical implementation. The development of laparoscopic linear staplers has enabled minimally invasive approaches to bariatric surgery, but there have been no comparison studies of the two current 6-row devices. We investigated the effects of mineral water fortified with folic acid, vitamins B(6), B(12), D and calcium on folate concentrations in serum and erythrocytes, serum vitamin B(12) and plasma homocysteine concentrations in free-living subjects. Hepatitis B Virus Infections and Associated Factors among Pregnant Women Attending Antenatal Care Clinic at Deder Hospital, Eastern Ethiopia.

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Although positioning systems such as the Global Positioning System (GPS) have been shown to be useful, we cannot assume that all devices deployed in the area (or most of them) will have positioning capabilities by themselves. In this study, experiments were pursued to identify and analyse the CRKL phosphorylation site(s).

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Acid gastric secretion released by insulin in anesthesitized rats Additionally, we investigated the loosening and alignment of implants from X-ray films.

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To determine nationally representative estimates of the incidence of peripartum stroke and intracranial venous thrombosis and to identify potential risk factors for these conditions. Here, we show that transient expression of Gata3, Eomes, and Tfap2c in mouse fibroblasts induces stable, transgene-independent trophoblast stem-like cells (iTSCs).

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We tested the hypothesis that earlier extubation attempts would decrease length of hospital stay and BPD. Determination of 136 pharmaceuticals and hormones in sewage sludge using quick, easy, cheap, effective, rugged and safe extraction followed by analysis with liquid chromatography-time-of-flight-mass spectrometry. One of these components is attributable to functional groups that react rapidly with chlorine, while the other reflects transformations of slowly reacting chromophores that arise following the depletion of the fast chromophores.

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N-acetyl-cystein pretreatment was again found to attenuate the activation of caspase-3 and -9. The effect of dietary zinc status on biliary metal excretion of rats. The AIDS epidemic is increasing the demand on all levels of health care staff to provide care compassionately and safely to people with AIDS and HIV infection. It was found that the conjugate provides siRNA delivery to murine myotubes differentiated in vitro.