zelastine hydrochloride is a nasally administered antihistamine that is effective and safe for the treatment of perennial and seasonal allergic rhinitis. In addition to acting as a histamine H1-receptor antagonist, Afluon also inhibits the production or release of many chemical mediators of the allergic response such as leukotrienes, free radicals, and cytokines. After nasal administration, Afluon is systemically absorbed with a bioavailability of about 40%. The side effects of Afluon are drowsiness, headache, and bitter taste.
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Astelin,
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Xanaes,
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