Ezetimibe and Atorin combination is used together with a proper diet to treat high cholesterol and triglyceride (fats) levels in the blood. This medicine may help prevent medical problems (eg, heart attack, stroke) caused by clogged blood vessels. It is also used to treat a condition called homozygous familial hypercholesterolemia (HoFH).

Ezetimibe is a cholesterol absorption inhibitor and Atorin is an HMG-CoA reductase inhibitor, or statin. These medicines will reduce the absorption of cholesterol from foods and the production of cholesterol in your body.

This medicine was available only with your doctor's prescription.

The Atorin/ezetimibe combination (Liptruzet(R)) was withdrawn from the United States market on June 2, 2015.

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Diterpenes as lead molecules against neglected tropical diseases. Moreover, pregnancy is drawing interest for preserving ovarian reserves in post-chemotherapy affected women, especially of younger ages. We studied eight foldable IOL models with optics made of six different acrylate/methacrylate polymers: Acrylens ACR360 (loptex), AcrySof MA60BM (Alcon), MemoryLens U940A (Mentor), 92S and 92C (Morcher), Hydroview H60M (Storz), HydroSof SH30BC (Alcon), and ISH66 (Corneal). Enhanced teaching of screening mammography using an electronic format. To evaluate the long-term functional status and quality of life of infants and children who have received extracorporeal life support (ECLS), and to determine how and when death occurred.

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Additional confirmative diagnosis may be possible by morphological and molecular confirmation of resected histopathologic specimens. VSD appears either as an isolated cardiac defect without other abnormalities or with several complex malformations.

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A model of polarized Madin-Darby canine kidney (MDCK) epithelial cells grown on filters was used to test for the presence of apically or basolaterally secreted factors on the growth of non-virulent (XL1-Blue) and uropathogenic (J96) strains of Escherichia coli (E. On the basis of these results, a new category-learning model is proposed that makes no a priori assumptions about category structure and that relies on procedural learning and memory.

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Clinical papers included observational studies and trials involving direct interaction between an investigator and human subjects. Contribution of Fe, Zn and niacin remained low for most groups, and thiamin, vitamin B6 and folate for some groups.

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Effect of centrifugation on the storage properties of platelets. For the majority of cancers, including many malignancies of the gastrointestinal tract, our current means of diagnosis and treatment of the tumors are grossly insufficient. There was no significant excess of cancer in target organs, i.e. Our studies show the functional reconstitution of a protein from the sum of its parts. Central to the new approach is empowering women and providing them with more choices through expanded access to education and health services and promoting skill development and employment.

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There is increased recognition of various forms of ocular pathology associated with mutations or other malfunctions involving TTR and RBP, warranting a greater understanding of mechanisms of transcriptional and translational control for these two proteins. In this randomized, double-blind, cross-over study, DHA or placebo capsules, were given daily to 10 patients, 5mg/kg for 2 weeks then 10mg/kg DHA for the next 2 weeks (or placebo).

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In addition, we determined the chromosomal localization of a second putative calcium-sensing receptor, CaS, for inclusion in the LOH studies. Patients carrying at least one mild mutation are considered to be pancreatic sufficient (PS) and carry an overall prognosis that is vastly superior to CF patients with PI.

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Apoptosis is the major mechanism by which eukaryotic organisms eliminate potentially dangerous, superfluous and damaged cells. This interaction seems to be the major factor in occlusal and cervical wear. Sociality, age at first reproduction and senescence: comparative analyses of birds. Everyday exposure to multiple chemicals, most of which are present indoors, may contribute to increasing prevalence of asthma, autism, childhood cancer, medically unexplained symptoms, and perhaps other illnesses. Nonsense mutations in the rhodopsin gene that give rise to mild phenotypes trigger mRNA degradation in human cells by nonsense-mediated decay.

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Characterization of a novel fructosyltransferase from Lactobacillus reuteri that synthesizes high-molecular-weight inulin and inulin oligosaccharides. A systematic review and meta-analysis was conducted to study risk factors of T2Es following EVAR to identify risk factors and measure their dedicated strength of association. Functional recovery was evaluated by measuring the time rats spent in completing the motor task.

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D-Exo treatment markedly increased expression of p53 and increased binding of p21 to CDK2 in the MCF-7 cells but not in NHMEC. Mechanism of plant growth stimulation by naphthenic Acid: effects on nitrogen metabolism of phaseolus vulgaris L. Mosses as model systems for the study of metabolism and development.

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(H3O)3Sb2Br9: the first member of the M3E2X9 structure family with oxonium cations. Co-immunoprecipitation analysis of differently tagged DGKdelta1 and DGKdelta2 proteins showed that they were able to form homo- as well as hetero-oligomers. Normal pregnancy is associated with systemic cardiovascular adaptation.

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Soluble triggering receptor expressed on myelocytes-1 compared to procalcitonin in patients with infectious and autoimmune systemic inflammatory response syndrome. Bacterial carriers and diphtheria patients were examined for blood concentration of total glycoproteins measured by protein-bound hexoses and of fuco- and sialoglycoproteins.

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At each level of perfusion, ANG II was infused at progressively increasing concentrations ranging from 10(-11) to 10(-5) M. Fourteen patients with hormone refractory metastatic prostate cancer were treated with CaelyxTM 50 mg/m2 once every four weeks. Nausea is the most common postoperative complication of anesthesia. It appears that GRE imaging is useful in rapidly assessing aqueductal patency. Rapid assessment of tetanus vaccine-induced immunity in Bangladesh and the Gambia.

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Levels of evidence categorize available studies by study design. Ionizing radiation sensitivity of the ocular lens and its dose rate dependence. In this article we summarize Ub-dependent and independent selective autophagy pathways, and discuss regulatory mechanisms and challenges for future studies. We propose a clinical framework to stimulate discussion of lobectomy as an option for low-risk patients.

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Metabolomic data analysis becomes increasingly challenging when dealing with clinical samples with diverse demographic and genetic backgrounds and various pathological conditions or treatments. Several (but not all) of the reviewed articles indicated that custom-made orthoses are more beneficial for plantar fasciitis than over-the-counter orthotics. If the plasma membrane vesicles were diluted with water, a mixture of right-side-out and inside-out vesicles again was obtained.

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Maximal rate of heart rate increases during cycling at 100 W tracks reductions in exercise performance when training load is increased, but not performance improvements when training loads are reduced. A mutation in exon 6 of the adrenoleukodystrophy gene (P543L) was identified. The interaction between tumor cells and the local milieu where are homing has recently become the focus of extensive research in a broad range of malignancies. These results indicate that coupling TNF with alpha(V) integrin ligands improves its antineoplastic activity and supports the concept that vascular targeting is a strategy potentially applicable to different endothelial markers, not limited to CD13.

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Therapy is preventive: careful management and follow-up of children with recurrent or chronic otitis media with effusion. elegans genetics, we showed that all four compounds act as potent suppressors of mTDP-43 toxicity through reduction of the ER stress response.

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Analysis of the role of the leucine zipper motif in regulating the ability of AFAP-110 to alter actin filament integrity. We compared 56 patients with severe ICA atherosclerosis referred for carotid artery endarterectomy (CEA) with 56 age-matched control subjects free of severe atherosclerotic disease. Metabolic score--a simple risk marker in non-ST elevation acute coronary syndromes. The constitutional genotype frequencies of two SNPs (C3435T and G2677T) in the MDR1 gene in 112 healthy control subjects were investigated and compared with those of 96 patients with BEN.

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To evaluate differences in risk attitude across the domains of health and money for 2 types of respondents, patients and community members. The dome was resected, and the bladder was repaired in 2 layers after identification of the ureteral orifices. In contrast to conventional radiography, MRI can directly visualize the articular cartilage, synovium, menisci, and other intra-articular structures important to the functional integrity of joints. The reconstruction outcomes were excellent in 20 patients and good in 6 patients according to the criteria of Boyden et al.

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The safety and efficiency of onabotulinumtoxinA for the treatment of overactive bladder: a systematic review and meta-analysis. From January 2002 to June 2004, 122 patients underwent anterior cervical decompression, autogenous iliac bone graft and plate fixation. A report of a randomised, controlled trial of a hydrocolloid dressing used in the treatment of leg ulcers that were failing to heal. The pump-and-probe process induces a fourth-order optical response that is forbidden in a centrosymmetric media.

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These observations suggest that common genetic determinants may control sensitivity to estrogen-induced thymic atrophy, maintenance of thymocyte homeostasis, and immune function. There is a paucity of objective methods for evaluating trainee performance and comparing ERCP accessories. This article reviews the major types of oculorenal manifestations in systemic autoimmune diseases. muris are insensitive and typically are performed at postmortem examination. Chronic ethanol consumption reduces delta-and mu-opioid receptor-stimulated G-protein coupling in rat brain.

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STZ diabetes significantly increased DAG and total PKC activity in decidua (1.5- and 1.4-fold, respectively) and embryos (1.7- and 1.3-fold, respectively) on day 9.5. Diabetes mellitus occurs frequently in patients with pancreatic cancer and does not influence clinical features of pancreatic cancer. Mean TCD with 2 standard deviations for each gestational week were determined as reference values. Patient-Accident-Fracture (PAF) classification of distal radius fractures

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A knowledge-based system for cassette mutagenesis experimental design. Importantly, the ESRS was more suitable for predicting the short-term risk of stroke in the clinic. A monoclonal antibody raised against cytochrome b558 reacted specifically with the 22- to 23-Kd protein, the small subunit of this cytochrome. Internet pornography use can be compulsive, but evaluation of pathology underlying this is difficult to assess.

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Inhaled corticosteroid therapy improves exercise symptoms in asthmatic subjects. A loss in circulating Vgamma9Vdelta2 T cells was observed, indicating that acute HIV replication may influence Vgamma9Vdelta2 homeostasis. The Neighborhood Health Center Program and its implications for medical care. Impact of a pay-for-performance incentive on support for smoking cessation and on smoking prevalence among people with diabetes.

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Majority of our young male patients fell in low risk Framingham risk score but still they manifested with CAD. Combined proteome and transcriptome analyses for the discovery of urinary biomarkers for urothelial carcinoma. An increase in serum free calcium concentration was observed in rats treated with 31.80 mg/kg fenvalerate. Medium term results with the Vanguard device appear to be at least equivalent to open repair with regard to morbidity and mortality.

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The developed method has the potential to serve as a non-destructive, sample-thrifty, and time saving tool to realize more realistic, practical dose-depth distribution of proton beam compared to conventional in vitro cell viability assessment techniques. Average nucleotide identity and digital DNA-DNA hybridization values among the three taxa were greater than the thresholds for bacterial species delineation, indicating that they belong to the same genomospecies. tularensis recovered from the blood of infected mice was in plasma rather than leukocytes. Nicotine is a developmental neurotoxicant and neuroprotectant: stage-selective inhibition of DNA synthesis coincident with shielding from effects of chlorpyrifos.

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Here we show that in the embryonic chick, Shh is expressed transiently in prechordal mesoderm, and is governed by unprocessed Nodal. Corin defects may contribute to major diseases such as hypertension, heart failure, pre-eclampsia, and kidney disease.

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An improved model of homogeneous nucleation for high supersaturation conditions: aluminum vapor. High membrane contrast is achieved and distinction of NPs with different chemical composition is possible at first sight. The cyclic incidence pattern is robust even if there is epidemiological interference due to cross-immune protection, which is observed in the epidemiological data as negative correlation between epidemics per MP serotype. Exposure of macrophages to these particles in isolation led to the release of tumor necrosis factor alpha and prostaglandin E2.

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The new species had been assigned to Leptolalax dringi and Leptolalax gracilis in the past. The epidemiology of septic shock in French intensive care units: the prospective multicenter cohort EPISS study. Part 2: distribution of families by number of children below age 16 by union republic

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Aurora kinases regulate mitosis and are commonly overexpressed in leukemia. Bands corresponded to monomeric forms of lung surfactant proteins. The free-energy surfaces provide a clearer understanding of the transitions not only between local minimum-energy states but also between the folded and unfolded states, even though the simulation involved large conformational changes. Radiological tests allow to identify the great majority of them and to perform an effective treatment. All methods correctly predict the qualitative trends in the EIEs related to the different isotope substitutions.

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We have characterized these plasmids and constructed their physical maps. To evaluate the impact of granulocyte-macrophage colony-stimulating factor (GM-CSF) or placebo on the durations of intravenous (IV) antibiotic use, hospitalization, neutropenia, and fever, as well as remission rates, after high-dose melphalan (HDM) without stem-cell transplantation (SCT) in patients with multiple myeloma (MM).

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Despite the complex nature of revision knee arthroplasty, cases utilizing an algorithm to balance the extension and flexion gaps, with increased implant constraint when necessary, can aid in obtaining a good outcome. Different income information as an indicator for health inequality among Japanese adults. Development of aberrant crypt foci involves a fission mechanism as revealed by isolation of aberrant crypts.

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Effects of NMDA receptor antagonists on olfactory learning and memory in the honeybee (Apis mellifera). Using a newly developed task paradigm we explicitly separated the processing steps (encoding, mental rotation proper and object matching) required by mental rotation tasks and additionally modulated the amount of spatial orientation information that had to be processed. For the nasal absorption studies, enoxaparin formulated with different alkylmaltosides was administered nasally to anesthetized rats and absorption of the drug was determined by measuring plasma anti-factor Xa activity.