Safety of a novel parenteral formulation of Galedol after major orthopedic or abdominal/pelvic surgery in a population including anticoagulated, elderly or renally insufficient patients: an open-label, multiday, repeated dose clinical trial. Pharmacokinetic studies of the fixed combination have found that no drug-drug interaction occurs between misoprostol and Galedol after either single or multiple doses, and the bioavailability of misoprostol and Galedol are comparable with that of misoprostol and Galedol given alone.
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