Klindan is used to treat certain types of bacterial infections, including infections of the lungs, skin, blood, female reproductive organs, and internal organs. Klindan is in a class of medications called lincomycin antibiotics. It works by slowing or stopping the growth of bacteria.

Antibiotics such as Klindan will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

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It also exerts immunomodulatory and antiangiogenic effects, as well as potent antitumor bystander effects, making it an ideal candidate for a new anticancer gene therapy. The different hypotheses of monogenic, mixed-monogenic-polygenic and polygenic inheritance as well as a pure environmental model were tested.

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We demonstrate here that this technique allows the imaging of the protein layers that result from the specific capture of antibodies by arrayed peptide probes with a spatial resolution of 0.45 microm. Symptoms of gastro-oesophageal reflux are frequent during treatment with an NSAID, but the NSAID-related gastro-oesophageal reflux-inducing effect has not been demonstrated. Aromatic DNA adducts in foundry workers in relation to exposure, life style and CYP1A1 and glutathione transferase M1 genotype.

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Early-childhood trauma is strongly associated with developing mental health problems, including alcohol dependence, later in life. This method uses the statistics and distribution of global feature of fingerprint images so that it is robust to image quality and local changes in images. Radiotherapy increased the tumor uptake of doxorubicin by a factor of two to four, with drug being redistributed farther from the vessels in the tumor periphery and located around vessels in the central parts of the tumor.

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At 16-28 degrees C the transport of cathepsin D to lysosomes is inhibited in a temperature-dependent manner. The sensor was successfully used to detect paraoxon and parathion down to a concentration of 1 x 10(-7) and 8.5 x 10(-7) M respectively. Confirmation power of computer tomography for suspected mediastinal tumors We describe a patient with severe OSA who developed transient contrast encephalopathy after elective coiling of an anterior communicating artery aneurysm.

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Prognostic variables in hairy cell leukemia after splenectomy as initial therapy. Epilepsia partialis continua: aetiology, semiology and prognosis in a Spanish adult cohort.

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The patient suffered for 1 yr from intermittent but progressive pain in his right upper arm and shoulder area. The themes that emerged from the interviews were: Awareness of testicular disorders and their screening, and help-seeking intentions for testicular symptoms. Recognition of AFR is important in these cases owing to the implications for management and post-operative patient satisfaction. The purpose of this study was to examine the efficacy of using thiosulfate to ameliorate the ototoxic effects of cisplatin. A fraction of radial glial cells expressing RC2 and Pax6 are also immunoreactive for Geminin and Cdt1.

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Here, we present a patient with acute subhepatic-retrocecal appendicitis in whom the clinical and US findings mimicked acute cholecystitis. Homology-dependent RNA silencing occurs in many eukaryotic cells.

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Individuals in no form of employment or education were classed as unemployed. To analyse the changes in epidemiology, outpatient and emergency department clinical care, and outcomes of patients treated for acute heart failure (AHF) in Spanish hospital emergency departments (HEDs) between 2007 and 2014. In study 2, the same servings were compared with water as an accompaniment to a bread meal. In the case of structural integrity of the skull, haematogenous spread or extension from adjacent structures, especially the sinuses, are the most common sources of infection.

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Once the existence of hepatopetal arterial collaterals had been confirmed in the remaining patients, the shunt was occluded by coil embolization. In this chapter, we introduce how to design and generate miRNA tough decoy inhibitors with an adeno-associated viral construct. These findings are relevant regarding the feasibility of rituximab in maintenance treatment and may also offer a rationale for the treatment of antibody-mediated autoimmune diseases with rituximab. There appears to be a positive correlation between the increase in ability to synthesize proteins at 4 degrees C and the increase in freezing resistance (survival at -10 degrees C). Cubic and hexagonal In(2)O(3) can be obtained from In(OH)(3) and InOOH, respectively, while size and morphology can be maintained to a certain extent.

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The lack of a reliable method for theoretical prediction of nanoporous anodic alumina films obtained from non-familiar electrolytes prompted the search of a viable solution to this problem. Diffusion-weighted MRI in herpes simplex encephalitis: a report of three cases. Lewis Y oligosaccharide has a terminal alpha1,3-linked fucose residue and elevation of Lewis Y level is seen in many epithelial cancers.

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citrate) and undissociated acid molecules, with the amounts of each determined by the acid dissociation constant (pKa) and the pH of the solution. High dietary salt intake exacerbates Helicobacter pylori-induced gastric carcinogenesis.

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In the present study, serial analysis of gene expression (SAGE) data from patients with OED were compared to normal controls to identify differentially expressed genes (DEGs). These experiments demonstrated a close relationship between the permeability of HM or YHMP skin and vasoconstrictor activity in humans. The process of initiation of activation and its perpetuation result from complex, often interrelated series of signalling mechanisms which converge on this effector cell. Centrosome amplification is frequent in cancer, but the underlying mechanisms remain unclear.

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However, humans and mammals are unable to synthesize n-3 PUFAs because they lack the n-3 desaturase gene fat-1 and must therefore obtain this type of fatty acid through their diet. The latter cells lacked evidence of myoepithelial differentiation but were best highlighted by immunostaining for high molecular-weight cytokeratin (34 beta E12). In this diagnostic test, 1170 participants underwent a 75-g oral glucose tolerance test. Further support also is provided for the usage of level-dependent HPDs during recreational shooting activities (i.e., at a shooting range).

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The results showed that high mobile phone output power is more frequent in rural areas whereas the other factors (length of call, moving/stationary, indoor/outdoor) were of less importance. Repeated and semantic encoding resulted in increased recall accuracy, with word repetition showing a greater effect when using a semantic encoding task. The epitheloid haemangioendothelioma rarely occurs extravascularly with less than 15 such cases reported in the literature. The findings of this unique analysis highlight the potential for website and app developers to merge user requirements with evidence-based content to ensure that information on infant feeding is of high quality.

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HLA-B27 positivity was associated with better outcomes irrespective of axSpA subdiagnosis. The purpose of this study was to determine whether warming of exercising legs improves exercise capacity in patients with cardiac disease and low exercise tolerance.

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Between the two cell types, the number of the mature cells was more significantly increased than the immature cells. Intrathecal dexamethasone decreased lumbar spinal COX-2 levels after incision, and an intrathecal COX-2-selective inhibitor did not reduce the COX-2 upregulation. Effects of co-substrates on biodegradation of pyrene by ten bacterial strains After immunizing mice with live cells from human livers, we isolated 54 hybridomas with binding activities to human cells and identified the corresponding antigens for five mAbs via screening on a protein microarray of 1058 unique human liver proteins.

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Apropos of changes in the nervous system, liver function and their interrelation in children following epidemic hepatitis Grade 4 in manual muscle testing: the problem with submaximal strength assessment. Interstitial (cornual) pregnancies occur rarely, estimated at 1 for every 2500 to 5000 live births.

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We recently reported that MEPE protects cells from DNA damage-induced killing. This pattern of nodulation persists when McCall and Peking seedlings are cultivated together in plastic growth pouches. Several medications that work through a variety of different mechanisms may be prescribed safely and effectively as antiandrogen therapies in the dermatology arena. The relationship between health-promoting behaviors and resilience in patients with chronic kidney disease.

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Incorporation of radioactive amino acids into the alpha and beta chains of hemoglobin in systems of different complexities A short description of the principles of MALDI-TOF MS is provided, followed by examples of its application and a discussion of its potential use in cyanotoxin research. The pore-forming toxins typically transform from soluble, monomeric proteins to oligomers that form transmembrane channels.

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Strategies to improve angiogenesis may facilitate the function recovery after stroke. Both wild-type and dcc heterozygous mice exhibited sensitization at this time.

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We show instead (1) that B7-2 binds the two receptors more weakly than B7-1, (2) that, relative to its CTLA-4 binding affinity, B7-2 binds CD28 2- to 3-fold more effectively than B7-1, (3) that, unlike B7-1, B7-2 does not self-associate, and (4) that, in contrast to CTLA-4 homodimers, which are bivalent, CD28 homodimers are monovalent. Relationship quality is the most frequently assessed construct in the intimate relationships literature. The care of a patient whose foot had become infected with gas gangrene is described. The data show a possibility for the interactions in the striatum of the corticofugal signals from different cortical areas with each other and with the ascending afferent signals. A radioimmunoassay which employed this antiserum and a tritiated antigen was established.

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They reached peak concentrations during vitellogenesis and courtship, remained high throughout the nesting season, and then declined to a nadir after the last clutch. quinquefasciatus aquatic habitats were overlaid onto the LULC maps generated in ArcInfo 9.1. The model is derived from a stochastic differential equation (SDE) based on the logistic equation, adding a stochastic term for the sloughing events and measurement noise. Influence of human leukocyte antigen class II alleles on susceptibility to Entamoeba histolytica infection in Bangladeshi children.

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This was accomplished by acquiring data at various time delays from the R wave throughout the cardiac cycle. Environmental stressors such as maternal psychosocial stress in pregnancy activate the stress response cascade that in turn drives the increase in the cellular energy demand of vital organs with high metabolic rates such as, in pregnancy, the placenta. The practice of routinely giving oral iron in such patients seems safe from an immunosuppression drug-interaction standpoint. The manifestations of reperfusion injury include arrhythmias, myocardial stunning and micro-vascular dysfunction, in addition to significant cardiomyocyte death.

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In this report, a revised method for defining and labeling laryngeal framework parameters is proposed. Retrospective comparative study of primary intracoronary stenting versus balloon angioplasty for acute myocardial infarction.

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Stability study of the optimised formulation showed that the tablets were stable at accelerated environmental conditions. The ability to bank fish embryos by cryopreservation could be crucial for preserving species diversity, for aquaculture (allowing circannual fish farming), and for managing fish models used in human biomedical research. law enforcement officers in the line-of-duty: situational context and predictors of lethality. Amplification and expression of the cyclin D1 gene in anal and esophageal squamous cell carcinomas. The findings are detailed and support the concept that if the symptoms of pain and dysfunction in patients with clicking can be treated successfully by conservative, nonsurgical modalities, it is generally not necessary to correct the internal derangement with surgery.

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Concurrent paclitaxel with upper abdominal RT is well tolerated at dosages that have substantial activity. We describe the parasitological kinetics and histopathological and immunological alterations in platelet-activating factor receptor-deficient (PAFR(-/-)) and wild-type mice after a single Strongyloides venezuelensis infection (subcutaneous inoculation of 500 L3 larvae). Peroxovanadate induces alpha 1B-adrenoceptor phosphorylation and association with protein kinase C. Chronic nicotine caused functional upregulation of nAChRs selectively in MHbVI cells, but did not change nAChR function in MHbVL. This study assessed the routine histologic sensitivity for current infection in patients with atrophic gastritis, with and without intestinal metaplasia.

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Fluorescence micrographs of Anabaena cylindrica filaments are presented for comparison. The analysis was performed in PBMCs from 8 cynomolgus monkeys from Philippines and from Mauritius both at protein level by flow cytometry and at transcriptional level by RT-PCR. Er:YAG laser application to the sandblasted porcelain flattened the roughness, and the effects of SP and SSP were similar. Effects of pH and Ethephon on Betacyanin Leakage from Beet Root Discs. Controlled release of paclitaxel from biodegradable unsaturated poly(ester amide)s/poly(ethylene glycol) diacrylate hydrogels.

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Conversely, malignant lesions, particularly in metastatic cases, were largely positive for DEK expression, which was partially associated with genomic amplification. A comparative study on direct and indirect electrochemical oxidation of polyaromatic compounds. Analysis of ataxia-telangiectasia mutated (ATM)- and Nijmegen breakage syndrome (NBS)-regulated gene expression patterns.

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The objective of this study is to test whether NCCM stimulates NPCs within their native environment, and whether combined stimulation with NCCM and addition of BMSCs has a synergistic effect on extracellular matrix production. Serum was analyzed for PBDEs, phenolic metabolites, and thyroid hormones.

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Results were compared with the karyotype determined through invasive procedures or at birth. The RSHBG.SHBG complex is rapidly activated by estradiol to stimulate adenylate cyclase, with a resultant increase in intracellular cAMP. After purifying the enzyme from human liver, a subfractionation into differently sialylated forms was obtained using MonoQ ion exchange chromatography. The algorithm has been tested on six cases of brain tumor resection, presenting a brain shift up to 13 mm.

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TMS was applied to the primary motor cortex, dorsal premotor cortex (PMd) and ventral premotor cortex (PMv) of the affected (M1AH, PMdAH, PMvAH) and intact (M1IH, PMdIH, PMvIH) hemispheres of patients and healthy controls in the setting of a simple reaction time (SRT) paradigm performed with the hand contralateral to the stimulated hemisphere. Labour migration and the single European market: a synthetic and prospective note. Laboratory sleep studies in posttraumatic stress disorder (PTSD) have not provided consistent evidence of sleep disturbance, despite apparent sleep complaints.

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A variety of origin patterns among the nerves to the lateral and medial gastrocnemius muscle, the nerve to the soleus muscle and the sural cutaneous nerve exist, necessitating the formulation of diversifying surgical strategies preoperatively and the meticulous and sequential dissection intra-operatively to ensure the lowest level of accidental injury. Improved tonsillar disposition of azithromycin following a 3-day oral treatment with 20 mg kg(-1) in paediatric patients. In epidemiological studies POPs have positive associations with serum markers of nonalcoholic fatty liver disease (NAFLD) and together with obesity synergistic association with insulin resistance.

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Food intake was obtained from a 24-hour dietary recall administered by computer-assisted telephone interview using the multiple-pass method. There is a general assent on the key role of standards in Synthetic Biology. Two cases of pseudo-achalasia with lung cancer: Case report and short literature review.

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The posterior wall thickness and the septal thickness were positively correlated to blood pressure (p less than 0.001), disease duration (p less than 0.001), urinary albumin excretion rate (p less than 0.001), and negatively correlated to the heart variation during deep respiration (p less than 0.01). Mastering the technique of the rotation flap will allow a surgeon to repair a wide variety of cutaneous defects. Lyme borreliosis is the most important vector-borne disease caused by spirochetes within the Borrelia burgdorferi sensu lato (B. Ethics approval of the study was obtained from the Institution Ethics Committee.

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The identification of genes that contribute to human disease leads to functional studies of disease-associated mutations, and the use of genetically manipulated animals in these types of study are providing important insights into molecular mechanisms in vivo. However, experience of this technique in benign diseases is limited. Rod opsin mRNA levels and rhodopsin kinase protein levels were also significantly greater in the axotomized and NMDA-treated eyes compared with the sham-treated fellow eyes after the photic injury.

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MRI may show areas of bone contusion that further the understanding of the mechanism of injury, predict and confirm the presence of capsuloligamentous injuries. Human rights approaches now dominate the HIV prevention landscape across sub-Saharan Africa, yet little is known about how they are viewed by the populations they are designed to serve.

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The relevance of specific alterations of G protein signaling for both depression and antidepressant action will be discussed, as will the ability for n-3 PUFA to act either as an antidepressant or in concert with conventional antidepressants. The findings will be disseminated through scientific and professional conferences, and in peer-reviewed journals. The data demonstrate that COX-inhibitors can differentially regulate gene transcription in multiple, functionally distinctly cell types in the brain. A key to slower health spending growth worldwide will be unlocking innovation to reduce the labor-intensity of care.

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In men seropositive for HCV, statins were effective in reducing LDL levels and did not result in significant increases in ALT levels from baseline. BSA was more effectively adsorbed by macroporous ECAB at around pH 3 and the mechanism of the adsorption of BSA to the ECAB was ion exchange. Floral Induction in a Photoperiodically Insensitive Duckweed, Lemna paucicostata LP6 : Role of Glutamate, Aspartate, and Other Amino Acids and Amides.

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The team spirit that originated during the team time carried over into everyday work, resulting in a better relationship between the hospital and nursing home staffs. Relationship between putrescine content and density of ischemic cell damage in the brain of mongolian gerbils: effect of nimodipine and barbiturate.

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We performed a retrospective review of all CP muscle EMG reports from studies performed between January 1996 and June 2003. TG-enriched LDL ineffectively down-regulated cholesterol biosynthesis compared with control LDL at the same protein concentration, but was equivalent in sterol regulation when compared on a cholesterol basis. A number of C3 mutants were important for energy coupling, as indicated previously for several members of this activator family (, ).