Topical Liroken for actinic keratosis comes as a gel (Solaraze) to apply to the skin. It is applied to the affected area two times a day for 60 to 90 days. Apply Liroken gel at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use Liroken gel exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Do not apply Liroken gel to open skin wounds, infections, or red, scaly, or peeling skin.

Liroken gel is only for use on the skin. Be careful not to get the medication in your eyes.

Wash your hands before applying Liroken gel. Then use your fingers to gently smooth the gel onto each affected area. Use enough gel to cover the areas completely. When you are finished applying the gel, wash your hands again. Be careful not to touch your eyes or nose before you wash your hands.

Your condition may begin to improve after 30 days of treatment, but it may take up to 30 days after the end of treatment before you see complete healing of the affected area or the full benefit of Liroken gel. Continue to use Liroken gel even if your condition has begun to improve. Do not stop using the medication without talking to your doctor.

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The use of the operating microscope and microsurgical instrumentation has resulted in more-precise periodontal surgical procedures with less operative trauma and improved healing. Sequence analysis of the cbb3 oxidases and an atomic model for the Rhodobacter sphaeroides enzyme. Falls can increase patient morbidity/mortality and increase legal risk/cost for institutions. This study determines the mechanical properties of the apparently regenerated ligament. No cases of infection, exposure, extrusion, or graft removal were encountered, and enophthalmus, symmetry changes, or restricted movement were not observed during the follow-up period.

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Synchronous firing patterns under parameter uniformity, and asynchronous circuit firing are shown to be driven, respectively, by membrane and synapse silencing and reactivation, and maintained by the neuronal filtering property. Most of the isolated and analyzed compounds had not been previously reported from this species. In our clinical trial, advanced cancer patients were treated with CPT-11 on a dose of 350 mg/m2 at day 1 every 3 weeks. Since a second hyperosmotic stimulus is known to increase neuronal firing rate and activity, our results suggest that a correlation exists with intracellular mechanisms regulating vasopressin gene transcription.

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Study of the use of 3-d targeted radiotherapy to control silicosis related local lung cancer DNA sequencing and rRNA gene sequences showed transmission of P. The prediction is accompanied by an expression probability curve for visual inspection of the supporting evidence.

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To assess upper extremity functioning of children with unilateral transverse upper limb reduction deficiency, using standardized instruments, and to investigate their validity and reliability. Surface waves on a liquid-air interface excited by a vertical vibration of a fluid layer (Faraday waves) are employed to investigate the phase relaxation of ideally ordered patterns. As the MS-OCT method requires important computational resources, the number of multiple depth en-face images that can be produced in real-time is limited. Surgical pearl: punch technique to improve granulation over exposed tendons in chronic wounds. There have been few studies on the probiotic property of lactococci, since they are formally not considered to be natural inhabitants of the intestine.

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Currently, the principal indications for using US in OA include: delineation of changes within articular cartilage (AC) and demonstration of synovial and adjacent soft tissue pathology together with injection into OA joints under US guidance. This study demonstrates that alterations in the degree and position of unsaturation of bonds in the sphingoid backbone of d-erythro-N-octanoyl-sphingosine (Cer) affect the antiproliferative ability of ceramide analogs in breast cancer cells. Although mitral repair has improved the results of mitral valve surgery, its influence on combined aortic valve replacement has not been assessed.

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The Leu544Ile polymorphism of the growth hormone receptor gene affects the serum cholesterol levels during GH treatment in children with GH deficiency. We describe in this chapter the methods routinely used in our laboratory to stimulate, record, and analyze the activity of olfactory receptor neurons in moths or flies. To study role of modified computed tomography severity index in evaluation of acute pancreatitis and its correlation with clinical outcome. Safe-yield concepts historically focused attention on the economic and legal aspects of ground water development. Six months after surgery, the animals were examined using light and electron microscopic techniques, as well as via a battery of behavioral tests (motor, open field, and T-maze).

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Phylogenetic relationships among Chinese species of Morella (Myricaceae) are unresolved. A review of the literature on transposition flaps was performed with specific reference to the principles of single-stage transposition flaps, including rhomboid flaps and their variations, multilobed flaps, and the locations where transposition flaps are frequently executed on the head and neck. Interactive Effects of Temperature and UV Radiation on Photosynthesis of Chlorella Strains from Polar, Temperate and Tropical Environments: Differential Impacts on Damage and Repair.

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tritici, race 126-ANZ-6, 7) were incubated in a cell-free protein-synthesizing system. Identification of extracellular matrix metalloprotease 3 in the fetal membrane of the rat and its possible implication in the rupture of chorioamniotic membranes Improved efficacy, predictability, and safety of modern phacoemulsification have resulted in cataract surgery being considered as a refractive procedure. Thus, it is clear that the estimate of extent of atherosclerosis and its associations with major risk factors depends upon the method used to measure atherosclerosis.

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Data for capitals of Union Republics and cities with a population over one million Specimens recovered from the bandicoot Perameles gunnii, also collected from Tasmania, are the first reported from the intestine of a mammal. A range of inter-positional materials have been used to avert recurrence after gap arthroplasty in TMJ ankylosis. The results suggest a model for branch migration in which DNA is pumped out of the small end of each ring as ATP is hydrolyzed.

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Cancer of the buccal mucosa, palate and gingiva in Connecticut, 1935-1959. STAPLE algorithm has been adopted from image to signal analysis to compare algorithms on large, incomplete, and noisy data without manual ground truth. The crystal size distribution and morphology were analyzed using Malvern Mastersizer and Jeol SEM. Fragility fracture, peripheral arterial and coronary artery disease, calcific uremic arteriolopathy, mortality, intradialytic hypotension, parathyroidectomy, extraosseous calcification, markers of mineral metabolism, diet liberalization, phosphate-binder use, and muscle mass. Any tricuspid disease not amenable to repair thus necessitating replacement is an unfortunate situation since both the short and long-term results of valve replacement are suboptimal in regard to those of left-sided valve replacements, probably due to different structural and geometrical characteristics of right ventricle and the low-pressure venous system hemodynamics.

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A high proportion of dogs, which are apparently healthy, yet seropositive, may remain an important factor in limiting the outcome of zoonotic leishmaniosis control efforts. Structural and functional changes in this model are best correlated to peak deltaIOP and not to duration of IOP elevation, suggesting the existence of an IOP-related damage threshold.

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Coronary artery disease is associated with persistent lower quality of life in women. PTX induced apoptosis, decreased the proliferation and cell migration rates of ASCs and inhibited ASCs multipotent differentiation in both in vitro human ASC populations and ex vivo rat ASC populations with PTX treatment. Mainstream tobacco smoke causes paternal germ-line DNA mutation. We have studied the species and tissue expression of the 68kD sulfogalactolipid binding protein SLIP 1, originally detected in the male germ cells of the rat (Lingwood: Can. There exists significant variability in surgical approaches to degenerative scoliosis, and evidence to support a specific approach is limited.

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Interpersonal stress, coping strategies, depression, anxiety, and somatization were assessed via self-report. Autologous fat grafting (AFG) has been widely used to treat progressive hemifacial atrophy (PHA). Patients with contralateral neglect showed a strong tendency to start their cancellation performance on the right. Removing the genetic contribution to PSA levels may improve the ability of the remaining biologically-determined variation in PSA to discriminate between high and low risk of progression within men with identified prostate cancer. Furthermore, mitoK(ATP) channel blocker, 5-hydroxydecanoate (500 micromol/l), abolished the protective effect of SFA.

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The current study examined family burden and its correlates in a medium income country in South America. These results have implications that are relevant to the development of a safe rabbit hemorrhagic disease (RHD) vaccine and further illustrate the utility of the ALVAC vector system to elicit protective immune responses in nonavian species. Local accumulation of alpha-spectrin-related protein under plasma membrane during capping and phagocytosis in Acanthamoeba. Sensitivities of Z-PLUS compared to the PSG Consensus were 0.84 for Light Sleep, 0.74 for Deep Sleep, and 0.72 for REM. Post-operatively she had no sign of ischemia, and no thrill was palpated or auscultated.

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Recent elucidation of a new signaling pathway in skeletal muscle affecting fatty acid metabolism has implications for regulation of insulin sensitivity and glucose metabolism. These data suggest that the proper combination of DXR plus DDP should be in sequence with DDP first.

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Patterns of healthcare service utilisation following severe traumatic brain injury: an idiographic analysis of injury compensation claims data. Thus, it is possible to distinguish two areas in this ecosystem: the impacted and the natural. Its presence has been demonstrated in almost all groups of organisms, from plants, protozoa to people.

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To determine the frequency of Campylobacter jejuni infection in children suffering from diarrhoea/dysentery in the Department of Microbiology, Army Medical College and Military Hospital, Rawalpindi, from 29 August 2002 to 29 November 2002. The proposed method can judge unclear genotypings to be re-examined and also work well even when the number of clusters is unknown.

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Postweaning changes in the expression of chemerin and its receptors in calves are associated with the modification of glucose metabolism. Linear sweep (LSV), square wave (SWV) and differential pulse (DPV) voltammetry techniques were applied to study FBZ at a glassy carbon electrode, exhibiting a well defined irreversible oxidation peak at 1.15 V vs. Bone scans and gallium scans were initially positive and remained abnormal, despite a variable clinical course and repeatedly negative serology and blood cultures. Furthermore, it is worthy of note that low SHBG levels in follicular fluid were associated with atretic oocytes. For the first time, the present work was studied for the potential protective role of these kaurane-type diterpenes on mitochondrial oxidative stress induced by H2O2 in the human astrocytoma U373-MG cell line and in the rat adrenal pheochromocytoma PC12 cell line.

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Diurnal variation in serum insulin-like growth factor (IGF)-I and IGF binding protein-3 concentrations during daily subcutaneous injections of recombinant human growth hormone in GH-deficient adults. The PW6B95-D3 density-functional-plus-molecular-mechanics calculation with the MG3S basis set stands out as yielding excellent accuracy while still being affordable for very large clusters. Plasmacytoid dendritic cells inhibit pulmonary immunopathology and promote clearance of respiratory syncytial virus. Patients in whom no S-100 value exceeded 20 ng S-100 per ml during the course of the disease had a favourable outcome, whereas patients in whom one or several CSF samples contained more than 100 ng/ml became severely disabled or vegetative or died. Stimulation of cadmium uptake in relation to the cadmium content of plants.

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The distance, intermediate (1 m, 50 cm), and near (40 and 30 cm) uncorrected and corrected binocular visual acuity (VA), contrast sensitivity, depth of focus, and patient satisfaction were assessed more than 1 month postoperatively. Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome. Within 1 hr, viral RNA forms sedimenting in sucrose gradients at 42S, 30S, and 16S were present. Morphine caused a statistically significant, concentration-dependent increase in XII ACh release.

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Although isolate 814 produced reduced amounts of several major antigens including at least one Bvg-activated factor (pertactin), the molecular basis of this deficiency was found to be BvgAS independent since the defect persisted after the bvgAS locus of isolate 814 was replaced with a wild-type bvgAS allele. Lessons learned from a collaborative meeting to construct a palliative care protocol. Tumor necrosis factor (TNF) is a key mediator of arthritis and acts catabolically on bone by stimulating bone resorption and inhibiting bone formation.

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Considerable degradation of phytic acid occurs by 15 minutes of incubation in glucose culture medium, and very little is left by 3 hours. Mercury in feathers of little egret Egretta garzetta and night heron Nycticorax nycticorax chicks and in theirprey in the Axios Delta, Greece. Oncogenic transformed fibroblasts are characterized by extracellular superoxide anion generation through a membrane-associated NADPH oxidase. These body image concerns are key reasons why a woman will be motivated to pursue breast reconstruction. Pain can be reproduced by active flexion of the hip and by active raising of the straightened leg.

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Here we review the available cognitive/behavioral studies on TYR, to elucidate whether and when TYR supplementation can be beneficial for performance. Coexistence of an unrecognized tetanic cataract with a band opacity of the cornea The current study investigated the oral health condition among 5-6 years and 12-13 years children in Nawalparasi district, Nepal.

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Guidelines on diabetes, pre-diabetes, and cardiovascular diseases Inputs were modeled as distributions for probabilistic sensitivity analysis and expected value of perfect information (EVPI) analysis to estimate the expected benefit of reducing uncertainty regarding the decision of optimal treatment. MELAS Syndrome with Cardiac Involvement: A Multimodality Imaging Approach.

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In the current study the accuracy of the lymphoscintigraphic sentinel node biopsy was verified against the gold standard of radical inguinal dissection. Interval to recurrence of ABMD was determined by using Kaplan-Meier estimates. This investigation was aimed at the evaluation of holotopy, skeletotopy and sintopy of human liver in early fetal period. The clinical and electrocardiographic data, myocardial damage markers (troponin I, CK-Mb mass, myoglobin), and acute-phase reactants (high-sensitivity C-reactive protein, fibrinogen) were recorded. The combination of ZD6474 and cetuximab determined synergistic growth inhibition in all cancer cell lines tested as assessed by the Chou and Talalay method.

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We find some striking phenomena that random regime transitions could drive Wolbachia to extinction from certain initial states confirmed Wolbachia fixation in homogeneous environments, and mosquito releasing facilitates Wolbachia invasion more effectively when the regimes transit frequently. Details of his preoperative evaluation, metastatic work-up, and use of tumor embolization are described. Forced expression of c-Cbl did not affect GH-stimulated STAT5 tyrosine phosphorylation, nuclear translocation, nor binding to DNA but markedly abrogated GH-stimulated STAT5-mediated transactivation.

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To assess validity of the Nambour food-frequency questionnaire (FFQ) relative to weighed food records (WFRs), and the extent to which selected demographic, anthropometric and social characteristics explain differences between the two dietary methods. Reply to Letter: Comparing direct and video laryngoscopy for urgent intubation during chest compression. Correlation between the severity of acute hepatic necrosis induced by acetaminophen and serum aminotransferase levels in fasted and sucrose-fed rats. Changes in ocular and nasal signs and symptoms among air crew in relation to air humidification on intercontinental flights. This strain was substantially attenuated in virulence in vivo and yet retained intracellular vacuole integrity and a functional SPI-2 T3SS.

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Ultrasound biomicroscopic appearances of eyelid lesions at 50 MHz. Test with a bronchodilator aerosol in the evaluation of expiratory obstruction to the passage of air One-year, multicenter, open-label, single-arm study evaluating the safety and effectiveness of etanercept for the treatment of moderate-to-severe plaque psoriasis in a Canadian population. In the first round of screening, twelve zebrafish lines that carry a single copy of ET cassettes were characterized to have tissue- or cell-specific EGFP expression. Mercury emissions from coal-fired utility boilers vary in total amount and speciation, depending on coal types, boiler operating conditions, and configurations of air pollution control devices (APCDs).

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Pre- and postadministration of CDRI-08 ameliorated amnesic effect of scopolamine by decreasing acetyl cholinesterase activity and drastically upregulating the mRNA and protein expression of BDNF, Arc, and GFAP in mouse cerebrum. Then, to optimize the proposed method for radial pMRI, a reconstruction method that uses coil sensitivity information of multichannel RF coils is formulated. The A Allele of the Single-Nucleotide Polymorphism rs630923 Creates a Binding Site for MEF2C Resulting in Reduced CXCR5 Promoter Activity in B-Cell Lymphoblastic Cell Lines. Nurses trained on HAND using a simplified approach had reasonable sensitivity and specificity for RHD screening.

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Multiple maps to different targets can be simultaneously stored if we introduce target-dependent modulation of place cell activity. Effect of sodium iodate injection on the development of galactose cataract in the rat. Electron and immunoelectron microscopic observation revealed human SOD1- and ubiquitin-positive aggregates consisting of intermediate filaments in the anterior horn even from an early presymptomatic stage.

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Pharyngeal airway fiberoptic imaging was performed in 10 decerebrate cats to determine the effect of selective pharyngeal muscle activation on airway shape. Compared with adults, circulating leukocytes from human newborns (preterm and full-term gestations) and newborn rabbits (full-term gestation) have low resting levels of CD62L (L-selectin) and do not significantly increase surface expression of CD18 after inflammatory stimulation.

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Four Group I agents (Form Cresol, Cam Phenic, Eucaly Soft, GC Fuji Varnish), but not two Group II agents (Caviton, Canals-N), induced internucleosomal DNA fragmentation and activated caspases 3, 8 and 9 in HL-60 cells. Tackling complex cases in the drug-eluting stents era: where are we now? The quality of placebos used in randomized, controlled trials of lumbar and pelvic joint thrust manipulation-a systematic review. The endoscopic localization of a gastrinoma in the afferent loop of a gastrojejunostomy. Biological activities and medicinal properties of Gokhru (Pedalium murex L.).

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This hypothesis is supported by the fact that astrocytes secrete NGF in vitro and that NGF activity increases in these target areas following these same lesions. To test the hypothesis that the expression of certain growth factors and/or structural proteins is correlated with the biological behavior of cranial base chordomas. Reliability of mini-bronchoalveolar lavage for the measurement of epithelial lining fluid concentrations of tobramycin in critically ill patients. Feasibility of using otoacoustic emission measurements to determine the extent and type of hearing loss is discussed.

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Descemet Membrane Endothelial Keratoplasty for a Decompensated Penetrating Keratoplasty Graft in the Presence of a Long Glaucoma Tube. In this article, we hypothesize that a natural product, the fungal phytotoxin fusicoccin, can play a role as a stabilizer of interactions between 14-3-3 proteins and specific natural targets. Delayed ischaemic deterioration (vasospasm) was usually accompanied by an increase in CSF S-100 concentration after 4 days.

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There is a need to develop a public health policy in post-crisis countries to maintain the reduction in free-sugar consumption, and hence promote both general and dental health, by integrating the common risk factor approach into the social determinant framework. The components, key concepts and procedural steps of endodontic microsurgery as well as the prognosis and predictability of modern root-end procedures are presented in this review. Pediatric surgical counts Key words: pediatrics, counts, surgical, retained surgical items, policy.

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Glutathione peroxidase and glutathione were significantly decreased distally. The characterization of mono- and dimethylated 5-substituted uracils was re-examined.

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A secondary high-performance liquid chromatography assay measuring Cys-GlcN-Ins production was used to validate potential hits. Colchicine myoneuropathy in chronic renal failure patients with gout. ICC are the pacemakers of the gastrointestinal tract and are involved in the transmission of the neuronal signaling to the smooth muscles. Linear embryos were constructed by dissociating 4-cell embryos and recombining the blastomeres in a linear array.

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Subarachnoid hemorrhage (SAH) is a neurological emergency because it may lead to sudden neurological decline and death and, depending on the cause, has treatment options that can return a patient to normal. Felodipine could well have a significant role in the long term management of the patient with chronic cardiac failure. A fasciocutaneous island flap, 0.5 cm distal to the volar skin defect, was formed on the dorsal side of the same finger. Here we report that the acylated synthetic antimicrobial peptide Oct-CA(1-7)M(2-9) is safe and effective for treating naturally acquired canine leishmaniasis. Very few cases after intensive care unit (ICU) for extended burn injury were reported.

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Linear regression analysis showed a positive correlation between IL 17 and Ang II. Our findings call for increased attention to screening of and treatment for hypertension, along with continued prioritization of early ART initiation.

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Laser desorption/ionization mass spectrometry on porous silicon for metabolome analyses: influence of surface oxidation. By combining different approaches, such as contact-angle measurement, hydrophilic/hydrophobic chromatography, microelectrophoresis, adhesion assays and calculation of interaction energies, it was shown that electrostatic interactions predominate over hydrophobic interactions at the cell-iron oxide interface. In vitro myotubes lacking CD9P-1 or both CD9 and CD81 fuse with a higher frequency than normal myotubes. Similar to observations in kidney epithelial cells, depletion of cilium-localized septins by siRNA-based approaches inhibited ciliogenesis.

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Persistent elevation of aspartate aminotransferase (AST) due to the presence of macro-AST: Report of one case These cultured cells were found to originate from the donor by genotyping. To examine the relationship between gestational age and mental and psychomotor development scores in healthy infants born between 37 and 41 weeks.

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Pesticide databases provide Kd values for each chemical, but the values vary widely depending on the soil sample on which the chemicals were tested. Muscle samples were analyzed for muscle protein synthesis (MPS) and by western blotting analysis to assess the phosphorylation of p70S6K (Thr389), rpS6 (Ser240/244), and Akt (Ser473 and Thr308). Many were markedly hypermobile and could perform a number of flexible maneuvers. Insertion of a tracheoesophageal speech valve: a novel approach in a difficult situation.

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Research on barriers to TUC in dental care could be facilitated by employing qualitative or mixed methods designs and studies that evaluate the impact of changing such barriers on TUC provision. The inability of Muta Mouse model to reveal the mutagenic activity of MMS was confirmed in bone marrow cells, 14 days after treatment. Antibiotic susceptibility for screening of resistance isolates was done by the Kirby-Bauer method.