This drug is used to treat high blood pressure. It is also used to lower the risk of strokes in patients with high blood pressure and an enlarged heart. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains two medications: Losart and hydrochlorothiazide. Losart is an angiotensin receptor blocker (ARB) and works by relaxing blood vessels so that blood can flow more easily. Hydrochlorothiazide is a "water pill" (diuretic) that causes you to make more urine, which helps your body get rid of extra salt and water. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This drug may also be used to treat heart failure.

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Forest degradation is a global environmental issue, but its definition is problematic. The morphologies of the synthesized gold nanoflowers are controlled and fine-tuned by varying the synthetic conditions such as the concentration of reagents and the growth temperature. A complete loss of O(2) sensitivity occurred up to 22 degrees C in Lycopersicon but only up to 6 degrees C in Scrophularia. Cardiovascular disease is often present in patients with newly diagnosed type 2 diabetes. We find a large number of new genes integrated into GGI networks throughout vertebrate evolution.

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The present results indicate that the NSCs in SVZ of the neonatal mouse can give rise to neurons in the OB and astrocytes in the cortex in early adulthood, but not generate progeny cells residing in the hippocampus. Constitutive versus regulated SNARE assembly: a structural basis. A rare case of carcinoma cuniculatum of the nasal cavity et paranasales sinuses is presented.

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Omecamtiv mecarbil dosing guided by pharmacokinetics achieved plasma concentrations associated with improved cardiac function and decreased ventricular diameter. We prove any deterministic partially observable Markov decision processes (POMDP) can be represented by a minimal, looping hidden state transition model and propose a heuristic state transition model constructing algorithm. Ablation of postinfarction ventricular tachycardia guided by isolated diastolic potentials.

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The electrophysiological integrity of the adult rat spinal cord was assessed at the lumbar, lower cervical and cortical levels after the animals sustained a severe contusion injury at the mid-thoracic level (T8) and received either carbon filament cultured with fetal spinal cord tissue implants, fetal tissue implants, or carbon filament implants alone. Changes in body composition during the first year after kidney transplantation are modulated by gender, energy intake, steroid doses, the occurrence of acute rejection, and delayed graft function. We examined the first and second landings of a drop vertical jump for differences in kinetic and kinematic behaviors at the hip and knee. In this network, the features that are extracted in CNN are classified through the deep network SAE.

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The data indicate declines in the number of marriages, births, and deaths between 1983 and 1984. Production of the C3 protein was demonstrated by radiolabeling and immunoprecipitation, and this also was stimulated by TNF-alpha. Behavioral depression in the swim test causes a biphasic, long-lasting change in accumbens acetylcholine release, with partial compensation by acetylcholinesterase and muscarinic-1 receptors.

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Localization and number of cleaved caspase-3-positive and single-stranded DNA (ssDNA) - positive cells were evaluated using dual-label immunohistochemistry with anticleaved caspase-3 and anti-ssDNA antibodies. Nonhistone nuclear proteins specific to certain mouse embryonal carcinoma clones having an inactive X chromosome. This study provides a promising new (68)Ga-labelled compound based on a commercially used kit for imaging the functional hepatocellular mass. Topical calcineurin inhibitors, such as tacrolimus, not only complement existing treatment options but also overcome some of the drawbacks of topical steroid therapy and fulfill the long-term needs of patients in preventing disease progression. Interferon, a growing cytokine family: 50 years of interferon research.

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Many of the articles found on our list have shaped the way we practice hand surgery today. This study aims to pilot implementation of the Baby Friendly Community Initiative (BFCI), a global initiative aimed at promoting optimal infant and young child feeding practices, to determine its feasibility and effectiveness with regards to infant feeding practices, nutrition and health outcomes in a rural setting in Kenya.

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T3 inhibits the calcification of vascular smooth muscle cells and the potential mechanism. These methods are based upon a sufficient statistic and therefore are considered proper statistical alternatives to the more descriptive epidemiological measures such as (in)directly standardized mortality (morbidity) ratios. An integrated biomechanical analysis of normal stair ascent and descent.

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Debridement associated with primary closure using Redon drains (RD) is an effective treatment, but data on RD management and antibiotic treatment are scarce. The main vortex that forms during left ventricular filling was tracked during two-three successive cardiac cycles, and its core vorticity was determined at a sampling rate up to 80 duplex images per heartbeat.

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The response to LT was observed in patients with high levels of HC, T, AOA and 6-keto-PGF1 alpha. The sleep-onset rapid eye movement (REM) period (SOREMP), the hallmark of narcolepsy, may be a specific state and not the simple anticipation of REM sleep.

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Investigation of high amplitude pressure oscillations generated by boundary driving in shaped resonators has been carried out both theoretically and experimentally. We review our 8-year experience with endoscopic removal of eroded gastric bands. The sensitivity of the LP-DBDI source was found to be about 40 times higher than that of the conventional APCI source.

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Cumulated activity for each radiopharmaceutical was calculated from a compartmental model based on the known biologic behavior of the compound. The study highlights important factors associated with PICU readmissions that can be incorporated into efforts to reduce mortality and resource utilization associated with readmission of critically ill children. Airborne microorganisms in a rearing henhouse for layers during vaccination Effect of Balloon-Expandable Transcatheter Aortic Valve Replacement Positioning: A Patient-Specific Numerical Model.

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These data provide insight into how 12-MSWS translate to meaningful functional limitations in MS. This is a general review of migration, including both international and internal migration, in the former Yugoslavia before its breakdown into constituent countries in the early 1990s. Selumetinib has been studied in combination with docetaxel in phase II randomized trial in previously treated patients with advanced lung cancer. Total polyposis of the gastrointestinal tract with facial skin pigmentation (Peutz-Van Dyke-Jeghers syndrome) Tumor biomarkers and targeted therapies are the new face of precision medicine, so it is essential for all physicians caring for cancer patients to understand and assist patients in understanding the role and importance of such markers and strategies to target them.

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Here, we demonstrate that the fission yeast HP1 protein Swi6 exists as a single highly dynamic population that rapidly exchanges in cis and in trans between different heterochromatic regions. AA anastomoses were classified as having unidirectional flow, having bi-directional flow, or being non-functional, depending on whether the hemodynamic equator reached a returning vein to one, both, or neither twin, respectively. We sought to investigate patient outcomes following incidentally detected cervical adenocarcinoma in situ after loop electrosurgical excision procedure or cold knife cone biopsy performed for the treatment of high-grade cervical intraepithelial neoplasia.

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The unpredictable interactive (either additive or synergistic) effects of the drugs used simultaneously have far-reaching implications on child health and development given the pervasive use of multiple drugs in our society. Presentations covered item response theory and assessment of test bias, construction of item banks and computerized adaptive testing, and the different ways in which qualitative analyses contribute to the definition of construct domains and the refinement of outcome constructs. Treatment expectancies, patient alliance, and outcome: further analyses from the National Institute of Mental Health Treatment of Depression Collaborative Research Program. Propolin H inhibited the proliferation of human lung carcinoma cell lines in MTT assay, and a significant G1 arrest was observed to occur in a dose-dependent manner at 24 h of exposure in H460 cells. We also examined synchronized anatomic differences between brain regions to gain insight into the plasticity of neural networks underlying stress susceptibility.

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The recovery of methyltransferase activity in vacuole-enriched fractions equalled that of the cytosolic marker enzyme glucose-6-phosphate dehydrogenase. We consider how advances in the cognitive neuroscience of addiction offer an alternative conceptual and methodological approach to studying the psychological processes that characterize addiction, and how such advances could inform treatment process research. The major recipient structure of the nucleus accumbens is the ventral pallidum. The role of epithelial-mesenchymal transition in oral squamous cell carcinoma and oral submucous fibrosis.

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The incremental benefit of duplicate sampling compared to single sampling is low. At the emergency department, 2 hours after she had ingested Datura stramonium, she was agitated, with delirium, anxiety, and frightening visual and tactile hallucination of green turtles walking on her as well as auditory hallucinations.

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Therapeutic effect of sunitinib malate and its influence on blood glucose concentrations in a patient with metastatic insulinoma. Outcomes of chest wall resections in pediatric sarcoma patients. The only restriction on the procedure is that the number of groups be small, relative to the total number of tests performed.

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Metabolism of Tritiated Gibberellin A(9) by Shoots of Dark-grown Dwarf Pea, cv. These data further suggest the possible therapeutic effectiveness of GHB in brain ischemia, and indicate that the underlying mechanism of action involves non-immediate steps of the ischemia-induced cascade of events. The SCI group also had consistently lower frequencies than the able-bodied controls. A laboratory experiment confirmed that cyanobacteria increase the susceptibility of Daphnia to Caullerya, and suggested a possible involvement of cyanotoxins or other chemical traits of cyanobacteria in this process. Our results demonstrate the involvement of PKC, MAPK and NF-kappaB in AGE-induced BREC proliferation and VEGF expression.

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The influence of the surface area on the performance of plasma filters for dead-end mode of filtration is presented in this paper. The indiruhbin of the higher purity was attained by the simple experimental method.

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In addition, we demonstrate for two different cell lines that the increase in RasGTP is reflected by an increase in Ras bound to Gst-RBD. Development of a plant transformation selection system based on expression of genes encoding gentamicin acetyltransferases. Seven extremely low birth weight neonates who were admitted to a neonatal intensive care unit of a regional center between March 1987 and October 1992 had acute intestinal perforation.

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Light microscope, MTT assay, flow cytometry, gene analysis and Western Blot were applied to investigate the effects of baicalin on the cell proliferation, the cell cycle and the involved molecular mechanism. Tissue culture studies on the functional morphology of astrocytes Smoking prevalence, yearly incidence of initiation of smoking and average years of smoking were calculated in analysis.

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Optical coherence tomography has found that patients with DR often have diffuse retinal thickening, cystoid macular edema, posterior hyaloid traction, and tractional retinal detachment. Cone inner segments are much wider than the outer segments which taper distally. In both studies, EPBL was administered by gavage at 0, 50, 10, or 200 mg/kg doses. Effect of treating 223 asthma patients with xiaochuangao for 10 years

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Unusual diagnosis of a solitary thyroid nodule in the paediatric population: cervical thymic cyst. We performed a post hoc analysis of a prospective multicentre study of critically ill hematology patients, in 17 intensive care units in France and Belgium. Our results highlight the fact that patients with HBV and HCV dual infection related chronic liver disease have a more aggressive course. Water distribution data for the cellulose system were obtained by several techniques and were coordinated with calorimetric data. Experimental results showed that the smaller the period is, the shallower the depth obtained owing to the self-volume growth effect is.

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For the implantation of continuous ambulatory peritoneal dialysis (CAPD) catheters, both the laparoscopic technique and the use of an Oreopoulos-Zellermann catheter have been suggested to be preferable to the open technique using Tenckhoff catheters. Hyperammonemia was induced by oral administration of an amino-acid (aa) solution mimicking hemoglobin composition.

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It remains unclear, however, how they handle the extensive variability inherent to speech, and how they process multiple linguistic functions that share the same acoustic parameters. Studies in albino Wistar rats showed that the expression of melanopsin is diurnal at both the mRNA and protein levels.

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The intra-mitochondrial cytochrome c distribution varies correlated to the formation of a complex between VDAC and the adenine nucleotide translocase: this affects Bax-dependent cytochrome c release. There is a lack of consensus in the literature as to how to define drinking outcomes in clinical trials. Although it is the ideal treatment, pituitary surgery is not always successful, and success is not always lasting. Also, treatment of these patients in the early-phase setting has a significant financial impact on the health care system.

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Small-to-moderate decreases in cold hypersensitivity up to 3 years after severe hand injuries: A prospective cohort study. The BioMINT unit is a mid-sized (1.2 L) reactor that operates on the principle of temporary immersion. Secondly, the scheme employs a method based on the SVM and the average intensity profile to isolate the teeth and detect root decay.

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Previous studies have indicated that chronic hypergastrinaemia increases the risk of colorectal cancer and cancer growth and that interruption of the effects of gastrin could be a potential target in the treatment of colorectal cancer. Combined with myosin inhibition studies, we identify genes that depend on nuclear tension for their regulation. The parathyroid tumor and recurrent thymic carcinoid tumor were removed completely together with brachiocephalic vein, superior vena cava, pericardium and anterior chest wall. Further comparative studies of pectin esterase in relation to leaf and flower abscission. All measures (AIMS, BPRS, HPLC, and NRRA) showed a high degree of repeated test reliability.

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5 of 6 of the first group but none of the 9 episodes of the second group resolved. Expression of Homer, Shank, Spinophilin, Densin-180, and the small RhoGTPase related gene Rac1 and downstream target genes, Limk1, Cofilin1 and Rock1 were investigated 1 day (1d), 7 d and 14d after FS-stress exposure. Isolation and characterization of nudC from mouse macrophages, a gene implicated in the inflammatory response through the regulation of PAF-AH(I) activity. Families of youths with mental health needs face considerable burden in accessing timely treatment.

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myo-inositol (2.5 g.kg-1.day-1 in the drinking water) and T3 (30 micrograms.kg-1.day-1 s.c.) were given for an 8-wk period 3 days after diabetes induction. The role of respiration in modulating blood flow in the portal vein is unclear. Pelvic floor support is maintained and the ureters are not in danger. NEDA status was achieved in a small proportion of our cohort, and did not preclude cognitive deterioration. This chapter will address the following key questions: (1) Why are pediatric-specific models of pain care needed?

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Environmental exposure in northeast Corsica results in detectable chrysotile and tremolite fibre loads in the lung and parietal pleura of adult goats. The activity of tedizolid was greater than linezolid against strains of Staphylococcus spp., Streptococcus spp., and Enterococcus spp. Various materials have been used for this procedure and have a good safety profile.

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Cardiac parasympathetic reactivation after small-sided soccer games and repeated sprints in untrained healthy adolescents. Gamma Knife Radiosurgery for Uveal Metastases: Report of Three Cases and a Review of the Literature.

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The difference in lens density between the 2 eyes was also documented. This numerosity-time interaction is proposed to be due to a shared neural representation for numerical magnitude and time intervals in the parietal cortex. Management of these infections has become more challenging due to rising rates of multi-drug-resistant organisms and few new antibiotic options. A subgroup of 111 patients considered to have endometriosis as the only major infertility factor were also evaluated and compared among treatment options. Large releasable pool of synaptic vesicles in chick cochlear hair cells.

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These data confirm that TTA does reduce CTT in tCCL stifles in this model. AtArf1 complements yeast arf1 arf2 mutants and its GFP-fusion is localized to the Golgi apparatus in plant cells like its animal counterpart. Clostridium septicum gas gangrene in a previously healthy 8-year-old female with survival. However, limited information is available for underlying genetic architecture of longitudinal trend in EW.

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The formation of glucose 1-phosphate from glycogen and phosphate produces a controlled change of pH which can be measured by the changes in absorbance of phenol red added to the system. Nitrogen has profound effects on the electronic structure of GaAs, as only a few percent of N can drastically lower the band gap.