Losatan is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure may reduce the risk of strokes and heart attacks.

Losatan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to tighten. As a result, Losatan relaxes the blood vessels. A lower blood pressure will increase the supply of the blood and oxygen to the heart.

Losatan is also used to decrease the risk of stroke in patients with high blood pressure and enlargement of the heart. It is also used to treat kidney problems in patients with type 2 diabetes and a history of hypertension.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

• Tablet

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They correspond to the abilities of a patient to perform basic and functional tasks regardless of contextual factors (environmental and personal factors). Study of biologically active substances from Actinomyces for the purpose of their use in livestock raising. The ferric uptake regulator of Pseudomonas aeruginosa has no essential cysteine residues and does not contain a structural zinc ion. The ODS score, a positive straining test and high CRST values suggest that postdefaecatory incontinence is secondary to impaired defaecation. Reduced bone mineral density in patients with inflammatory bowel disease is thought to be due to disturbances in calcium homeostasis or the effects of corticosteroid treatment.

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A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease. Average cancer cancer incidence and mortality over the ten years were 24.1/105 and 15.9/105 respectively, and the overall ratio of mortality/incidence (M/I) was 0.69:1 (range 0.58-0.73).

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We show that attosecond pulse trains have a natural application in the control of strong field processes. In contrast, neonatal ZIP5 expression remained unchanged, but this protein was removed from the basolateral membrane of the enterocyte.

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Relationship between transient DNA hypomethylation and erythroid differentiation of murine erythroleukemia cells. Impairments in precision grip correlate with functional measures in adult hemiplegia.

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Treatment remains challenging in many companion birds due to the lack of information regarding prognosis and efficacy of antineoplastic treatments in these species. COX-2 expression is associated with an aggressive phenotype in ductal carcinoma in situ.

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Anticancer property of sediment actinomycetes against MCF-7 and MDA-MB-231 cell lines. However, a significant amount of projects are abandoned unfinished, which leads to substantial wastage of resources. Approximately, 50 percent of the sample met screening criteria for a comorbid mental health condition.

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The substantial differences in the magnitude of seed losses to ants and birds demonstrate the need for evaluation of seed removal on a wide range of species in any given ecosystem. mesenterica, total lysis of fibrin occurred within 60-90 minutes whereas in the renovascular basin the process took 30 minutes longer. The results suggest that productivity varies widely among hospitals as a function of staffing patterns, methods of organization, and the degree of reliance on nurse extender (NE) technicians. However, despite advances in the field of pharmacology with advent of newer and better antibiotics prevalence of the disease could not be abated. Insights into bonding interactions and excitation energies of 3d-4f mixed lanthanide transition metal macrocyclic complexes.

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Chlorhexidine is effective for monotherapy in AK and could be a good choice for initiating treatment. This study adds to the presently scant knowledge about non-genetic determinants or moderators of actual bitter food intake.

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The clinical utility of circulating neuroendocrine gene transcript analysis in well-differentiated paragangliomas and pheochromocytomas. In this 78-week, double-blind, placebo-controlled European study, patients were randomised to receive acarbose, titrated to a maximum dose of 100mg three times daily, or matching placebo. The main principle is based on modifying the topography of the X-ray CNT experimental setup before FIB-TOF-SIMS measurements by incorporating a square washer around the sample. Metastasis to the choroid was found most frequently, making the choroid the most common site of metastasis.

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Changing spectrum of sporadic acute viral hepatitis in Indian children. The pre-treatment and post-treatment ages for each case were noted as recorded on the corresponding study models. To investigate the association of recurrent aphthous ulcer (RAU) with Helicobacter pylori (Hp) infection and digestive diseases.

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Seasonal changes in spermatogenesis and testicular steroidogenesis in the male black bear Ursus americanus. Two domains of MyoD mediate transcriptional activation of genes in repressive chromatin: a mechanism for lineage determination in myogenesis.

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These results are consistent with the findings of other investigators suggesting that medications and psychotherapy for anxiety disorders may not be as effective for older individuals as they are for younger people. It is concluded that for routine transmission electron microscopy of, for example, negatively stained biologic specimens, a diode array scanner produces data good enough to obtain resolutions at a level normally expected. Pain intensity and functional-economic rating scale (Prolo scale) were unremarkable. Beyond 30 minutes after a single phototransformation or after the start of continuous red irradiation, phytochrome destruction commences. Polymorphisms in HLA-DRB genes were genotyped using oligoneucleotide arrays, and the magnitude of associations was determined by logistic regression analysis.

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Due to their proximity to the right lung, high anterolaterally positioned atrial screw-in leads carry a small but definite risk for right-sided pneumothorax. Quantification is also of added value for monitoring therapeutic efficacy, although this depends on the type of therapy that is installed.

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Non-suicidal self-injury (NSSI) commonly starts in adolescence and is associated with an array of negative outcomes. Nonuniform fluence profiles can also be used to further reduce dose delivered to normal tissues, though this strategy does result in higher dose levels delivered to a small volume of the CTV and normal tissues. However, the canvas of Ankrd6 expression does not match closely that of the three mouse Flamingo homologs, Celsr1-3 (Tissir et al., 2002). This was a multi-centered, double-blind, randomized controlled trial. Disruption of transforming growth factor-beta signaling through beta-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation.

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Several mechanisms exist through which microorganisms can develop resistance against antimicrobial drugs, of which the overexpression of genes to produce efflux pumps is a major concern. Calcifying epithelioma of Malherbe of the left preauricular area in a 10-year-old child Neurofibromatosis type 1 (NF1) is among the most common human genetic disorders, having a constellation of cutaneous and skeletal manifestations, intellectual impairment, and an increased risk for a variety of malignancies. Slow-cooling ice VI at 1.4 GPa gives essentially fully hydrogen-disordered ice VI.

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Lysine residues of the RLP were functionalized with norbornene acid as confirmed via 1H-NMR spectroscopy. Bangladeshi families are particularly motivated to participate in clinical trials despite variable comprehension of study concepts. While T lymphocytes were shown to be essential targets of GC therapy, at least in animal models of MS, the mechanisms by which GCs modulate T cell function are less clear.

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Smoking cessation is important for the prevention and therapy of PAD, and to this end, counseling by physicians and nicotine replacement therapy are useful and strongly recommended for patients with PAD. In this study, to elucidate the effects of group I fibers of the median nerve (MN) on the excitabilities of the brachioradialis (BR), we evaluated the changes in the firing probability of a BR motor unit after electrical conditioning stimulation (CS) to MN with a post-stimulus time-histogram technique in six healthy human subjects. The similarities of PgMV to other members of the Reoviridae are discussed. Our objective was to determine costs of surgery and to identify areas where cost reduction is possible.

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The Middle East is heavily impacted by blindness, and the problem there is augmented by an increasing incidence of diabetes in the population. However, the majority of prostate cancer survivors are not physically active.

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As a stress surrogate, isoproterenol was used to test retroconduction and reversal of drug-induced block. Two children, boys of 8 and 13 years, presented with measles-associated encephalopathy several years after kidney transplantation for congenital nephrotic syndrome. Immunohistochemical and ultrastructural examination demonstrated the expression of keratin and the desmosome-like junctional structure in the spindle cell components. An unusual case of collagenous gastritis was observed in a 37-year-old man who presented with profound weight loss, a feature that has not previously been emphasized. Nodular thyroid disease and thyroid malignancy: Experience at Polokwane Mankweng Hospital Complex, Limpopo Province, South Africa.

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Here, we conducted a pilot study in a tissue-mimicking flow phantom to explore the spatial aspects of droplet vaporization and investigate the effects of applied pressure and droplet concentration on image contrast and axial and lateral resolution. A Comparison of Techniques for Optimal Performance of Bronchoalveolar Lavage. A 38-year-old woman was operated on to remove a large tumor that replaced the left adrenal gland. Eighty-two hypertensive patients and seventy-eight normotensive individuals were evaluated.

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Concerns have been raised about the role nurses should play in deciding whether overseas patients are charged for NHS care. The paper concludes with a brief discussion of future trends in HRQL outcomes evaluation. The subtropical hilly red soil area in China is an important production base of foodstuffs and tropical and subtropical economical crops and woods, and also, is very important in carbon balance research because of its special ecological and geographic characters. Multi-organ dose evaluations and the effects of heterogeneous tissue dose calculations have been retrospectively evaluated following irradiation to the whole thorax and lung in non-human primates (NHP).

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Once within the regulated secretory pathway, all phogrin lumenal domain proteins were stored in functional granules for extended periods of time. Morphine was also effective in relieving pain in all three tests but with signs of considerable sedation.

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Operative data of a psychiatric internation unit in a general hospital of health public system in Buenos Aires City The Curia, directed by the Secretariat of State, includes 9 Congregations, 3 Tribunals, 12 Pontifical Councils, and offices that handle church affairs at the highest level. Lower level of synovial fluid interferon-gamma in HLA-B27-positive than in HLA-B27-negative patients with Chlamydia trachomatis reactive arthritis.

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Cancer Prognosis Defined by the Combined Analysis of 8q, PTEN and ERG. This was confirmed by extracting silicone tubing and silicone grease with DCM followed by MALDI-MS analysis. It is recognized as an important cause of recurrent pregnancy loss. It is found that the nasal staphylococcus carriage in donors depends on the level of specific and natural antibodies and on the coincidence between the staphylococcus antigen structure and the protein substance of the specific blood group factors. In normal kidney protein expression was found in the cytoplasm of proximal and distal tubular cells, in cells of the thick segment of the loop of Henle, and in urothelial cells of the pelvis.

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The objective of this study was to evaluate the clinical significance of associated autoimmune/autoinflammatory diseases in generalized vitiligo patients with respect to some general clinical variables, distribution pattern, disease activity and treatment response. Icariside II activated Akt signaling, which is required for its actions in osteoblasts.

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The matrix of concentrations of 16 elements in 27 plant samples of 7 species from 15 sampling sites of 2 rivers and concentrations of 15 elements and pH in water samples and 16 elements and pH in bottom sediment samples of these sites was submitted to numerical classification, which revealed that sampling sites from the rivers were differentiated by the value of factor 1 of principal component analysis (PCA), which was related to the pH of water, Ca, Cu, Mg, Mn, and Ni in water and Cd, Cr, Cu, Fe, K, Mg, Na, Ni, P, and S in bottom sediments. In order to compare these approaches, it may be useful to discuss them as quantitative descriptors of survival and transformation-like endpoints in cell cultures in vitro--a system thought to be relevant to modelling radiation hazard.

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The difference in the denaturation temperature of the I-E(k)-Hb betaH81Y mutant as compared with that of the I-E(k)-Hb wild-type at pH 5.5 was only slightly smaller than that at pH 7.4, in agreement with the increased stability at an acidic pH, a unique characteristic of MHC II. Administration of rabbit anti-thymocyte globulin during cardiopulmonary bypass: a novel approach to the highly sensitized cardiac transplant patient. Joint source and channel coding for 3-D scene databases using vector quantization and embedded parity objects. The VaccImm Server provides a convenient way to analyze properties of peptide vaccination in cancer therapy. Serious AEs, overall withdrawal, AE-related withdrawal and psychiatric adverse events (PAEs) were not significantly associated with BRV treatment.

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S100P is Overexpressed in Squamous Cell and Adenosquamous Carcinoma Subtypes of Endometrial Cancer and Promotes Cancer Cell Proliferation and Invasion. However, natural flea densities are sufficiently high to harm the more susceptible, juvenile cohort. A dynamic panel data model is used to estimate demand functions for fat, protein, alcohol, cigarettes and diversity of the diet.

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This reduction in cell expansion was not due to failure of the cells to maintain turgor since cells adapted to NaCl underwent osmotic adjustment in excess of the change in water potential caused by the addition of NaCl to the medium. The primary outcome was change from baseline of cell-associated unspliced HIV RNA. One category of telomere clones was found to contain internal, variant TAAGGG repeats. Highlight report: Validation of prognostic genes in lung cancer. Helical scanning was performed using 1-mm and 3-mm thick sections.

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Under the overlap condition, the central stimulus remained during the presentation of the peripheral stimulus and therefore participants need to disengage their attention intentionally in order to execute the saccade to the peripheral stimulus due to the preservation of the central stimulus. This case of cervicothoracic spinal cord compression caused by IgG4-related sclerosing pachymeningitis (IgG4-RSP) has never been reported in China with merely three case reports worldwide. Genetic analysis of a meningococcal population based on polymorphism of the pilA-pilB locus: a molecular approach for meningococcal epidemiology. The messenger RNAs of 15-LOX were determined by reverse transcription and the polymerase chain reaction (RT-PCR).

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Venoarterial ECMO was established in 7 patients, venovenous ECMO in 2 patients, and combined venoarterial and venovenous ECMO in 1 patient. Furthermore, molecular and genetic investigations are necessary for classification because a close correlation could be established between distinct CJD phenotypes, codon 129 genotypes of the prion protein gene, and the prion protein type.

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It is suggested that this auxin-stimulated incorporation of free monosomes into membrane-bound polysomes might involve increased utilization (through activation or synthesis) of messenger RNA(s) acting as template(s) for synthesis of secretable enzyme(s) involved in growth. Short-range synthetic aperture imaging at 633 nm by digital holography. A diet high in soy is associated with many health benefits, including reduced incidence of breast cancer.

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Values of initial stress in the microimplant-bone interface due to press-fit generated by immediately placed microimplant were very high in these limited and simplified three dimensional finite element models. Each of the life patterns influences each of the others, and changes that affect one member of the couple have a significant effect on the other. The performance of methods for correcting measurement error in case-control studies. Dose and timing of total-body irradiation mediate tumor progression and immunomodulation.

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Administration of amiodarone into the aortic root for persistent ventricular fibrillation after aortic valve replacement. The metatarsal cytochemical bioassay of parathyroid hormone: validation, specificity, and application to the study of pseudohypoparathyroidism type I. Anxiety and depression tend to present relatively soon and are often enduring whereas concomitant medical problems also present later. Peritoneal effluent markers of inflammation in patients treated with icodextrin-based and glucose-based dialysis solutions.