Topictal is a medicine used to treat epilepsy. These are also called anti-epileptic medicines.

It can also be taken to prevent migraine.

This medicine is only available on prescription. It comes as tablets or capsules.

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This review assesses the current state of knowledge regarding preclinical and clinical pharmacology for brain tumor chemotherapy and evaluates relevant brain tumor pharmacology studies before October 2006. A lumped parameter compartmental model for the cerebrovascular fluid system is constructed and solved for the general linear problem of a nonsteady flow with constant resistances and compliances. Antagonistic effects of high and low temperature pretreatments on the germination and pregermination ethylene synthesis of lettuce seeds. Bioartificial liver treatment reduces both serum bile acid concentrations and the hydrophobicity of the bile acid pool.

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These compounds with possible QQ ability hold the potential for use as anticaries drug leads and antibiofilm preventative medicine. Either D2 or D3 antisense oligodeoxynucleotides greatly attenuated the ability of apomorphine to inhibit dopaminergic neurons in vivo, an effect that was potentiated by simultaneous administration of D2 and D3 antisenses. Religiosity and teen drug use reconsidered: a social capital perspective. This response can be removed by Norflurazon treatment, without affecting the rest of the fluence response curve.There is also some activation of phytochrome by lower fluence rates of B, an effect which contributes to the overall inhibition of growth. No circulating antibodies were detected 4-5 months after experimental infection, although these horses still harbored infective larvae.

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Simultaneous treatment of trials of gastrointestinal strongylosis and monieziosis in cattle with a mixture of Thiabendazole and Niclosamide Structural medicine and structure-based drug design for prion diseases

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Transition metal dichalcogenide particles were previously quantified using the anodic (oxidative) particle coulometry method. It was concluded that the effect of delay frequency on the forgetting function is mediated by the effect of the reinforcer distribution, which influences discriminability by weakening stimulus control. Inversion of Correia Repeat Enclosed Elements in Neisseria gonorrhoeae. Twin pregnancy and the effects of prophylactic leave of absence on pregnancy duration and birth weight.

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These observations concerning the interactions of age and genetic changes in glioblastoma suggest that tumorigenic pathways to glioblastoma vary with the age of the patient and that future molecular marker studies should carefully evaluate the potential age-dependent prognostic effects of these biological variables. Excess tyrosine stimulates eumelanin and pheomelanin synthesis in cultured slaty melanocytes from neonatal mouse epidermis. Patient perspectives on barriers to accessing eye care and reasons they choose to seek care or not are presented. Feasible interventions for primary care that promote activity and decrease avoidant coping styles may improve outcomes. Specifically, the ZAS-N domain selected sequences similar to the canonical RSS nonamer, while ZAS-C domain selected sequences similar to the canonical RSS heptamer.

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Current therapeutic strategies focus on counteracting the cocaine effects directly on the dopamine transporter, through post-synaptic D(1), D(2) or D(3) receptors or through the glutamatergic, serotoninergic, opioid or corticotropin-releasing hormone systems. This article seeks to take a broad look at this tool in its current and historical perspective and examine how it can provide a stable foundation for improved physician-nurse communication, agreement on the plan of care, successful care transitions, and improvements in quality metrics, and reduced length of stay. Evaluation of the safety and efficacy of the Pipeline embolization device (PED) when used as second-line treatment for recurrent or residual, pretreated ruptured and unruptured intracranial aneurysms (IAs). Computer access to the medical literature has become more convenient than ever with MEDLINE and other bibliographical databases available on CD-ROM.

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Metastable resistance-anisotropy orientation of two-dimensional electrons in high Landau levels. Results from pyrolysis mass spectrometric and DNA amplification fingerprinting analyses underpinned the taxonomic status of clusters 2, 3 and 4 and suggested that the A. Data for the study were collected through a self-reported questionnaire that was distributed to 166 divers. The objectives of this study were to determine the proportion of women with risk factors receiving pre-pregnancy care in selected clinics in Selangor, their socio demographic features, the types of risk factors detected and their significance. Does the neuropeptide Y Y1 receptor contribute to blood pressure control in the spontaneously hypertensive rat?

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Evidence of an association between mannose binding lectin codon 54 polymorphism and adenoidectomy and/or tonsillectomy in children. Functional Brain Imaging in Cornelia de Lange Syndrome: Case Report and Literature review.

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Lethal leptospiral pulmonary hemorrhage: an emerging disease in Buenos Aires, Argentina. naturally contain effective materials for agglutinating and fusing particular cellular membranes through the sequential aid of acidic cell sap and alkaline seawater after disintegration of the giant cells. The role of non-invasive cardiovascular imaging in the assessment of cardiovascular risk in rheumatoid arthritis: where we are and where we need to be.

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Two new studies (see the related articles beginning on pages 357 and 370) use lamin A/C-deficient mice, which develop striated muscle disease, as a model to investigate pathogenic mechanisms. To date, there has been little information on the over-the-counter or prescription medicines that adolescents ingest for self-harm. Electric field and vibration-assisted nanomolecule desorption and anti-biofouling for biosensor applications. Seven of these mutated residues are absolutely conserved between AvrB and its nine homologues.

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AHP-based disinfectant can, therefore, be used in high containment laboratories working with FMDV, SVDV and related pathogens. Abrogation of normal cell cycle controls in tumor cells contributes to their inability to differentiate and the restoration of such controls in G1 can lead to the resumption of differentiation and terminal cell division.

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There is no evidence of the efficacy or safety of chlorobutanol-caffeine suppositories for the treatment of hyperemesis gravidarum. ICD-10 codes for the underlying cause of death on the original and the corrected death certificates issued by Akershus University Hospital were retrieved from the Cause of Death Registry for the period 1 May 2008-31 December 2009, once the Cause of Death Registry had processed the death certificates with the aid of the computer program ACME (Automatic Classification of Medical Entities).

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Results of pyrogenal treatment of patients with multiple sclerosis and disseminated encephalomyelitis As NBS showed lower production efficiency than did NAS, a larger amount of the NBS expression plasmid than of NAS expression plasmid was introduced during cotransformation, resulting in successful production of rNCL in the culture medium.

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Registration of the causes of death regarding perinatal mortality and particularly stillbirth by the CBS shows gaps, mostly due to incorrect reporting of the cause of death by the treating physician or autopsist, due to the fact that at the time of notification the morbid-anatomical diagnosis and/or laboratory data were not complete. Recent studies have demonstrated that CEA may function as a metastatic potentiator by different pathway, such as modulation of immune responses, facilitation of intercellular adhesion and cellular migration. We have exploited the observation that the rat MHC class I allele RT1-Aa, when expressed in the rat C58 thymoma cell line, effectively competes and prevents the endogenous RT1-Au molecule from associating with TAP. Greater knowledge about blood donation does not lead to donation.

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The calculated spectra reproduce the signs and approximate magnitudes of the near-uv CD bands of both RNase A and S. Aggregation and dispersion behaviours of halloysite nanotubes (HNTs) were influenced by pH. ABCA5 mRNA was detected in poorly differentiated colon adenocarcinoma (GI-112) and undifferentiated ovarian carcinoma (GI-102), but not in normal colon.

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Exposure of tissue to irradiation (300 krad) at different times during a 20-hour washing period severely inhibited the development of RNA polymerase activity during the early stages of washing. In Thailand, some have been studied but they did not cover the wide range of important factors. To analyze the mutation of TSC gene in two sporadic patients with tuberous sclerosis complex (TSC). Multiple messenger candidates and marker substance in the mammalian Merkel cell-axon complex: a light and electron microscopic immunohistochemical study. Evaluation of interactive toxicity of chlorophenols in water and soil using lux-marked biosensors.

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Technical limitations prevented scientists from obtaining accurate assessment of the mechanical properties of physiologically realistic matrices. Electrochemical DNA biosensor based on the BDD nanograss array electrode. Lipid phosphate phosphatase 3 participates in transport carrier formation and protein trafficking in the early secretory pathway. Effect of raloxifene on urinary incontinence: a randomized controlled trial. The efficacy and safety of the procedure, in-hospital clinical evolution and the occurrence of major adverse cardiac events in the first year were assessed.

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Obvious resistance of the protease Lon C-terminus to proteolysis indicates that this region of the enzyme molecule including its substrate-binding and proteolytic domains has a well folded structure. Correlation of maximum flexion with clinical outcome after total knee replacement in Asian patients.

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We suggest that this regulation of the sub-cellular localisation of extradenticle is important for the interactions between extradenticle and the homeotic selector proteins and that extradenticle is not simply a ubiquitously available cofactor. albicans binds human complement regulators in order to control complement activation at its surface.

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The influence of substrate stiffness gradients on primary human dermal fibroblasts. Comparison of body composition in black and white premenopausal women. Determination of residues of sulphonamide in eggs and laying hens. Although single-voxel proton MR spectroscopy is a noninvasive method that enables measurement of brain metabolite concentrations, it has been shown that physiologic brain motion causes inaccuracies in measurement of metabolite concentrations and increases the overall SD of the measurements when the stimulated echo acquisition mode (STEAM) is used.

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Diagnostic value of serum lipid and apolipoprotein parameters for the detection of a coronary risk even in the range of nonpathological serum cholesterol and triglyceride values Group 2 rats received standard pellet diet and 2 gm/kg body weight crude Parsley leaf ethanol extract for the entire experimental period of 8 weeks.

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The structures were established as phloyoside III, phloyoside I and cistanoside B. Development of artemisinin and its structurally simplified trioxane derivatives as antimalarial drugs. A boric acid solution enriched in 10B was applied to these mycelia.

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In particular, the lattice Monte Carlo method, combined with density functional calculations, was employed to explore the spontaneous supramolecular organization of this tripod-shaped molecule under surface confinement. The inner ear originates from an embryonic ectodermal placode and rapidly develops into a three-dimensional structure (the otocyst) through complex molecular and cellular interactions.

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The expression of thrombospondin (TSP) of hepatocellular carcinoma (HCC) was investigated by light and electron microscopic immunohistochemical studies, using an anti-human TSP antibody to HCC and liver specimens. Photosystem II membranes isolated from treated leaves were largely depleted of two proteins of 20 and 14 kilodaltons, which correspond to the extrinsic 23- and 17- kilodalton proteins of spinach functioning in oxygen evolution. However, c-HANPs exhibited significantly high stability in a physiological buffer and released the loaded drug, paclitaxel (PTX), in a sustained manner. Some biological activities of pigments extracted from Micrococcus roseus (PTCC 1411) and Rhodotorula glutinis (PTCC 5257). For depressive symptoms, a reduction in mean score of 0.15 was found for each year of increase in age.

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The impact of remote ischaemic preconditioning (RIPC) on major clinical outcomes in patients undergoing cardiovascular surgery remains controversial. Two hundred and eighty-three samples with a clinical suspicion for lymphoid neoplasms were received in FC laboratory and analysed using various lymphoid markers.

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We aimed to identify the possible clinical and laboratory predictors of calcinosis in a cohort of patients with a diagnosis of polymyositis (PM) and dermatomyositis (DM). Recent research has found evidence of an association between motor vehicle accidents (MVAs) or near miss accidents (NMAs), and excessive daytime sleepiness (EDS) or its main medical cause, Obstructive Sleep Apnea (OSA). Intravenous Esomeprazole 40mg is Effective for the Control of Intragastric Acid Levels Whether Given as a 3-Minute Injection or a 30-Minute Infusion. Altogether, our data demonstrate that the LXR-mediated induction of LPCAT3 primes human macrophages for subsequent eicosanoid secretion by increasing the pool of AA, which can be mobilized from phospholipids.

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Diffuse scattering from liquid solutions with white-beam undulator radiation for photoexcitation studies. Single application of GCS in orthopedic surgical or neurosurgical patients using venography showed no effect when compared to combined treatment of GCS and low molecular weight heparin. To this aim, we introduce a clustering method based on information theory, specifically designed to cluster genes according to their codon usage and apply it to the coding sequences of Escherichia coli and Bacillus subtilis. Via its complex network of connections with other cellular proteins, GRK2 contributes to the modulation of basic cellular functions-such as cell proliferation, survival, or motility-and is involved in metabolic homeostasis, inflammation, or angiogenic processes. Such an approach will not eliminate all postoperative readmissions but will likely have a major effect on readmission rates.

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In this review, various types of bioMMAs used as a VADS are described to show the latest advances and their diverse uses and potential applications in vaccine-related fields. Experiments performed in situ by adding exogenous protein 4.1 to permeabilized 3T3 cells show that this protein binds to microtubule and nuclear components. We examined infarct size and myocardial function in a porcine coronary artery occlusion/reperfusion model in CMT-3-treated and control animals. Comprehensive Monte Carlo calculations of AAPM Task Group Report No. To determine the frequency and site of distant infraclavicular metastases of nasopharyngeal carcinoma (NPC), the stage of the primary tumour at presentation of metastasis and the histological trends.

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Modeling of the catalytic core of Arabidopsis thaliana Dicer-like 4 protein and its complex with double-stranded RNA. FPT inhibition could be a novel, noncytotoxic method of treating ras dependent tumor growth. To guide the choice of a delivery strategy (or combination of strategies), reliable and standardized cost information for the different options is required.

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This study examined the effects of stabilized-rice bran (SRB) rich diet on responses to stress in rats. The APC bracket failed significantly more often than the control at initial arch wire insertion in both maxillary and mandibular teeth. Nurses were trained to identify severe protein-energy malnutrition using IMCI training materials.

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Purpose of the present work was to investigate thermoluminescent dosimeters (TLDs) response to intraoperative electron radiation therapy (IOERT) beams. Protein was localized using immunostaining with different polyclonal antibodies. Sarcoidosis is a disease of unknown aetiology, which may involve almost any organ. The value of mass roentgen studies for the early diagnosis of lung tuberculosis in comparison to other diagnostic methods We then combined immunoperoxidase labeling for Orx with immunogold-silver labeling for GABA or for tyrosine hydroxylase (TH) in DA neurons.

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On the other hand, the transcriptionally silenced variant could neither trans-silence nor trans-methylate homologous sequences, even after being in the same genetic background for generations and meiotic cycles. Support and training in the complex task of anticoagulation management may help to extend this efficacious prophylactic therapy to all patients who may benefit from it. Immobilization of the affected joint is an essential element of treatment. Staple-assisted, endoscopic Zenker diverticulotomy has been shown to decrease both cost of treatment and length of convalescence when compared with the standard open approach.

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Spermatagonial stem cells and cells in post-spermatagonial stem cell stages are the critical target cell populations of regulatory importance. We therefore evaluated the influence of potential mediators on the association between socioeconomic position, and prostate cancer-specific and all-cause death in prostate cancer patients. Uterine artery embolization (UAE) for fibroid treatment: results of the 4th Radiological Gynecological Expert Meeting

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Questions assessed professional development opportunities on bullying and sexual harassment prevention/intervention, personal definitions of these behaviors, and their perceptions of school norms regarding such behavior. In this work, we revealed that dying tumor cells induced by irradiation prompted PIA via a caspase 3 dependent mechanism. We tried primary resection and anastomosis with the aid of intraoperative irrigation of the dilated proximal colon.

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APA are involved in the pathogenesis of Libman-Sacks endocarditis usually associated with SLE. We evaluated the cardiac function of five patients with CPEO by means of carotid pulse recording and Doppler echocardiography. Care study Christine was admitted for a left total knee replacement under spinal anaesthesia.