Zafen is an everyday painkiller for a range of aches and pains, including back pain, period pain, toothache. It also treats inflammation such as strains and sprains, and pain from arthritis.

It's available as tablets and capsules, and as a syrup that you swallow. It also comes as a gel, mousse and spray that you rub into your skin.

Zafen is combined with other painkillers in some products. It's an ingredient in some cold and flu remedies, such as Nurofen Cold and Flu.

You can buy most types of Zafen from pharmacies and supermarkets. Some types are only available on prescription.

For under-17s, read our information on Zafen for children

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Viable fungi and bacteria in personal exposure samples in relation to microenvironments. The questioning of OSAS symptoms alone is inadequate to estimate traffic accident risk.

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Allergen-mediated mast cell activation is a key feature of ocular allergic diseases. The protective response against Treponema pallidum (Tp) infection of a DNA vaccine enhanced by an adjuvant CpG ODN was investigated. The method further revealed a singly and doubly phosphorylated peptide in dynamin III, analogous to the dynamin I sequence. Redundancy in the function of mitochondrial phosphate transport in Saccharomyces cerevisiae and Arabidopsis thaliana.

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We screened 143 patients with histopathologically proven OLP for prevalence of anti-HCV antibodies. To determine whether the varicocele grade is related to the degree of improvement in serum testosterone levels after varicocelectomy. Using kinetic techniques to measure regulation of myosin S1 binding to actin and fluorescently labeled Tm to directly measure Tn binding, we show that binding of Tn to both isoforms is similar (0.1-0.5 microm) and both produce well regulated systems. Therefore, it seems appropriate to monitor potassium levels when therapy of a responsive tumor is initiated.

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In total, eleven hospital disaster preparedness tools had been used in these 33 studies. This information may be relevant for prognostication and potential management strategies. Cyp26 Enzymes Facilitate Second Heart Field Progenitor Addition and Maintenance of Ventricular Integrity. Systematic methods for measuring outcomes after RC can identify areas of improvements on an ongoing basis, which can be used to initiate timely corrective measures.

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However, FGF signaling was shown to be crucial for stem cell self-renewal and for proper hematopoietic poststress recovery. A major reason for this postulate is avoidance of hyperthyroid crisis. The extracellular protein Reelin sends signals to various downstream molecules by binding to its receptors, the apolipoprotein E receptor 2 (ApoER2) and very low-density lipoprotein receptor and exerts essential roles in the neuronal migration and formation of the layered neocortex.

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Databases on the distribution of species can be used to describe the geographic patterns of biodiversity. After 4 doses of paclitaxel, the patient developed erythematous patches on both forearms and both thighs. Responses were compared for passive (reading numbers) and active (adding numbers) conditions.

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To determine the effect of a sympathetic block at C7 on cluster headache. Two-dimensional gel electrophoresis resolves total cellular protein from Euglena gracilis klebs var bacillaris Cori into 640 polypeptides, 79 of which are induced by light exposure. Pressure probe technique for measuring water relations of cells in higher plants. COX-2 inhibitors may have an effect on serum PSA levels in patients with biochemical progression after RT or RP. The induced apoptosis was abrogated by guanosine which replenishes GTP pools through the guanosine salvage pathways, while it was enhanced by hypoxanthine, a competitive inhibitor of GPRT.

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Central conduction time in SSEPs did not correlate with seizure or developmental outcome. In this work, we have combined femtosecond broadband transient absorption experiments with state-of-the-art molecular simulations to provide mechanistic insights into the ultrafast and efficient population of the triplet state in the UVA-activated pyrimidine anticancer drug 4-thiothymine. Frequency distribution of the circumference of the chest in primary and middle school children in the urban area

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The sites of predilection are the neck, interscapular region, inframammary area and abdomen. The polymodal association areas of the primate cerebral cortex are heavily interconnected and play a crucial role in cognition. This review summarizes the necessary solution-phase methodologies, the status of solid-phase synthesis of oligosaccharides, and combinatorial synthesis of oligosaccharide libraries. The cancer stem cell theory postulates that tumors are sustained by a select cell population with specific features, such as self-renewal ability and the capacity to give rise to a heterogeneous mass of tumor cells. In contrast to the lung, the uterus expresses an 80-kd PDE-5 isoform.

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Occurring on a minutes-to-hours time scale, these changes are accompanied by increased direct apposition of both somatic and dendritic membrane, the formation of dendritic bundles, the appearance of novel multiple synapses in both the somatic and dendritic zones, and increased neural occupation of the perivascular basal lamina. The matrices allowed these teeth to be split into buccal and palatal halves and to be reassembled.

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Using a reaction time (RT) task, the biceps brachii muscle was investigated in five healthy subjects to determine whether EMG in the initial phase of activity is dependent upon the direction of movement, i.e., elbow flexion and forearm supination, and/or influenced by the presence or absence of warning signal. Saving womens lives: evidence-based recommendations for the prevention of postpartum haemorrhage.

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Cortical blindness in a patient with eclampsia: posterior reversible encephalopathy syndrome. A systematic, Support Vector Machine-based method has been proposed in this study for such purpose.

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Spinal epidural abscesses: conservative treatment for selected subgroups of patients. Much interest has been devoted to the efferent activities of the afferent fibers, which probably act on the target tissues by secreting a variety of neurotransmitters. On the other hand, society will experience an increase in orphans, destabilization of the family unit, and a reduction in family income.

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BAVM samples had a gene expression pattern that was distinct from those of control brain samples. Antigen-specific versus total immunoglobulin synthesis: total IgE and IgG1, but not IgG2a levels predict murine antigen-specific responses. Despite concerns expressed about the lack of scientific data on the safety and efficacy of marijuana, no clinical trials on the medical uses of marijuana have been completed in Canada. The relationship between traumatic coagulopathy and intraoperative SBS was evaluated.

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Nine patients with T1 or T2 carcinoma of the posterior wall of the hypopharynx (UICC 1987), who were treated surgically between 1984 and 1994, were studied. OCT showed a persistent unsealed and un-reattached internal limiting membrane.

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Most existing spatiotemporal multi-dipole approaches for MEG/EEG source localization assume that the dipoles are active for the full time range being analysed. Risk of death was highest among females, and among the oldest and youngest population subgroups. Health technology assessment (HTA) currently focuses on efficiency, rather than equity, on the basis that its primary objective is to maximize population health.

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Recent reports have described damage to myelinated fibers in the central nervous system (CNS) in patients with temporal lobe epilepsy (TLE) and animal models. This investigation was conducted to the Isfahan Neurosciences Research Centre. We used the same materials and methods that were originally employed in tests of human infants to assess whether cotton-top tamarin monkeys can extract abstract algebraic rules. To investigate the effect and mechanism of blockade of STAT3 signaling pathway by JAK specific inhibitor-AG490 on invasion and metastasis of human highly metastatic pancreatic cancer line SW1990 in vitro.

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Regression analyses identified several strong and independent correlates of violent criminality. By the experience of the 1st case, we could diagnose the following 2 cases as having enteric anisakiasis. The circumstances around the raids suggest that factors such as reduced mating opportunities, number of males relative to that in the neighboring community, and the strength of bonds among males could play a role in the timing of such actions. The data of 29 patients with HER2 positive MBC were collected from July 2008 to July 2010 at our department.

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Papillary thyroid carcinoma in patients with RET proto-oncogene germline mutation. A study of ankle and toe pressure prediction following aortofemoral bypass. While the value of the critical surface potential varies with the electrolyte concentration and the Hamaker constant, it apparently corresponds to a common value of about 10 kT for the height of the primary maximum of the interaction potential. A k-means clustering analysis of the two cultivars revealed groups of genes with similar or dissimilar expression profiles. The effects of the target compounds on the vasodilation activity were tested in the isolated preparation of mice thoratic aorta.

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Differences in lower extremity kinematics between a bilateral drop-vertical jump and a single-leg step-down. One hundred twenty eyes of 120 patients underwent pars plana vitrectomy with or without internal limiting membrane (ILM) peeling for macular edema with foveal hemorrhage due to BRVO with a minimum 12 months of follow-up. The EndoPearl is an adjunct to bioabsorbable interference screw fixation in the femoral tunnel in anterior cruciate ligament (ACL) reconstruction. The study showed that acute knee joint pain leads to hyperalgesia and facilitated temporal summation in the infrapatellar fat pad and in muscles located distant to the injection site, in subjects with no history of knee pain.

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A novel extrapolation model, based on frequencies of patients visits at MS clinics, was used to estimate the overall prevalence of MS. Lung microvascular adaptation in infants with chronic lung disease. Suspecting ethylene oxide hypersensitivity, the third hemodialysis session incorporated a biocompatible dialyzer that was sterilized with gamma irradiation, not ethylene oxide. This sensitive method has broad applications, both in the area of free radical medicine and in the pharmacological study of aspirin and its metabolites. To determine the prevalence of peripheral arterial disease (PAD) in type 2 diabetes patients and to measure the strength of the association of selected risk factors.

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The outbreak happened in school with low rubella-containing vaccination coverage. In mixed glial cell cultures from cerebral cortices of newborn rats, endotoxin induces inducible nitric oxide (iNOS), nitric oxide (NO), and interleukin-1 beta (IL-1 beta) production in microglial cells. The sensitivity and specificity of the algorithm for detecting referable diabetic retinopathy (RDR), defined as moderate and worse diabetic retinopathy, referable diabetic macular edema, or both, were generated based on the reference standard of the majority decision of the ophthalmologist panel. AQ4, an antitumor anthracenedione, inhibits endothelial cell proliferation and vascular endothelial growth factor secretion: implications for the therapy of ocular neovascular disorders. We hypothesized that these cells might potentially be able to convert the inactivated form of Hx (Hxi) to active Hx (Hxa) in vitro, mediated by cellular ecto-ADPase.

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The c-Met-immunopositive cells were also localized to reactive astrocytes. Increases in airway responsiveness to histamine precede allergen-induced late asthmatic responses. Retinoids cause apoptosis in pancreatic cancer cells via activation of RAR-gamma and altered expression of Bcl-2/Bax.

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Substantial improvements were observed in conditional survival at one and three years after diagnosis compared with survival at diagnosis. We show that the rate of penetration of liquids into the porous capillaries can be controlled by the laser polarization, which determines their morphology.

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Prevalence of pre-diabetes, diabetes, pre-hypertension (pre-HT), and hypertension (HT) in children weighing more than normal. The results obtained demonstrated how transport distances influence the ecological benefit of recycling.

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This technique was also used to quantitatively assess the amounts of hypophosphorylated Rb throughout the cell cycle in these representative cell lines. Here we show that GRK2 mutants impaired in Galphaq/11 binding (R106A, D110A, and M114A), bind effectively to mGluR1a, but do not mediate mGluR1a adaptation. The administration of AVP-I to the SN-salt hypertensive rats, with or without furosemide administration, significantly decreased mean BP. We found that TIP120B gene was induced in C2C12 myoblasts when these cells differentiated into myotubes, whereas TIP120A gene expression was down-regulated.

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This study extends previous in vitro work and confirms the selectivity of deoxyglucose for viable cells over necrotic regions and for hypoxic cells over normoxic regions in vivo. The effects of color of lighting on the behavior and production of meat chickens.